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Cancer immunotherapy : immune suppression and tumor growth /

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking the...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology
Group Author: Prendergast, George C; Jaffee, Elizabeth M
Published: Academic Press/Elsevier,
Publisher Address: Amsterdam ; Boston :
Publication Dates: 2007.
Literature type: eBook
Language: English
Subjects:
Cancer > Immunotherapy
Antineoplastic Agents > therapeutic use
Tumors > Immunological aspects
Ca ncer > Immunoterapia
Agentes antineopla sicos
Neoplasmas
MEDICAL > Oncology
HEALTH & FITNESS > Diseases > Cancer
Neoplasms > therapy
Immunotherapy > methods
Electronic books
Online Access: http://www.sciencedirect.com/science/book/9780123725516
Summary: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic dru
Carrier Form: 1 online resource (xiii, 409 pages, [4] pages of plates) : illustrations (some color)
Bibliography: Includes bibliographical references and index.
ISBN: 9780123725516
0123725518
9780080521855
0080521851
Index Number: RC271
CLC: R730.51
Contents: Part I: Principles of Cancer Immunobiology -- Introduction -- Cancer Immunoediting: From Immune Surveillance to Immune Escape -- Immunosurveillance: Innate and Adaptive Anti-Tumor Immunity -- Cytokine Regulation of Immune Tolerance to Tumors -- Immunological Sculpting: Natural Killer Cell Receptors and Ligands -- Immune Escape: Immunosuppressive Networks -- Part II: Cancer Therapeutics -- Cytotoxic Chemotherapy in Clinical Treatment of Cancer -- Targeted Therapeutics in Cancer Treatment -- Concepts in Pharmacology and Toxicology -- Cancer Immunotherapy: Challenges and Opportunities -- Cancer
Introduction / George C. Prendergast and Elizabeth M. Jaffee -- Cancer immunoediting : from immune surveillance to immune escape / Ryungsa Kim -- Immunosurveillance : innate and adaptive antitumor immunity / Masahisa Jinushi and Glenn Dranoff -- Cytokine regulation of immune tolerance to tumors / Ming O. Li and Richard A. Flavell -- Immunological sculpting : natural killer cell receptors and ligands / David A. Sallman and Julie Y. Djeu -- Immune escape : immunosuppressive networks / Shuang Wei, Alfred Chang, and Weiping Zou -- Cytotoxic chemotherapy in clinical treatment of cancer / Rajesh T
Immunotherapy and cancer therapeutics : why partner? / Leisha A. Emens and Elizabeth M. Jaffee -- Immune stimulatory features of classical chemotherapy / Robbert G. van der Most, Anna K. Nowak, and Richard A. Lake -- Dendritic cells and coregulatory signals : immune checkpoint blockade to stimulate immunotherapy / Drew Pardoll -- Regulatory T cells in tumor immunity : role of toll-like receptors / Rong-Fu Wang -- Tumor-associated macrophages in cancer growth and progression / Alberto Mantovani, Paola Allavena, and Antonio Sica -- Tumor-associated myeloid-derived suppressor cells / Stephanie

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