Screen LibraryTelomerases：chemistry, biology, and clinical applications
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| Group Author: | ; |
|---|---|
| Published: |
John Wiley & Sons,
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| Publisher Address: | Hoboken, N.J. |
| Publication Dates: | c2012. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | x, 308 p., [16] p. of plates: ill. (some col.) ; 24 cm. |
| ISBN: |
9780470592045 0470592044 |
| Index Number: | Q55 |
| CLC: | Q55 |
| Call Number: | Q55/T277 |
| Contents: |
Includes bibliographical references and index. The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehuda Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA processing, trafficking and protein interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere-length homeostasis / Joachim Lingner and David Shore ... "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence ... |