Screen LibraryNanoscale fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology /
Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: th...
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| Corporate Authors: | |
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| Group Author: | |
| Published: |
William Andrew, an imprint of Elsevier,
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| Publisher Address: | Kidlington, Oxford : |
| Publication Dates: | [2018] |
| Literature type: | eBook |
| Language: | English |
| Series: |
Pharmaceutical nanotechnology series
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| Subjects: | |
| Online Access: |
https://www.sciencedirect.com/science/book/9780128136294 |
| Summary: |
Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to improve yield and entrapment efficiency. Written by a diverse range of international researchers, the chapters examine characterization and manufacturing of nanomaterials for pharmaceutical applications. Regulatory and policy aspects are also discussed. This book is a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about how nanomaterials can best be utilized. |
| Carrier Form: | 1 online resource (676 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780128136300 0128136308 |
| Index Number: | RS192 |
| CLC: | TQ46 |
| Contents: | 1. Fabrication of polymeric core-shell nanostructures -- 2. Emulsification-diffusion method to obtain polymeric nanoparticles: two decades of research -- 3. Tools and Techniques for the optimized synthesis, reproducibility and scale up of desired nanostructures from plant derived material and their role in pharmaceutical properties -- 4. Scale up of biopharmaceuticals production -- 5. Physicochemical and morphological characterization of pharmaceutical nanocarriers and mathematical modelling of drug encapsulation/release mass transfer processes -- 6. Biopharmaceutics and pharmacokinetics of multifunctional nanoparticles -- 7. Technological delivery systems to improve biopharmaceutical properties -- 8. From physicochemically stable nanocarriers to targeted drug delivery: in-vivo pharmacokinetic, pharmacodynamic and biodistribution studies -- 9. Sterile dosage forms loaded nanosystems for parenteral, nasal, pulmonary and ocular administration -- 10. Quantitative Characterization of Targeted Nanoparticulate Formulations for Prediction of Clinical Efficacy -- 11. Analytical tools for reliable in vitro and in vivo performance testing of drug nanocrystals -- 12. Application of one-step affinity purification of drug-binding proteins with practical magnetic nanoparticles to drug discovery -- 13. Molecularly Imprinted Polymers as Separation Tools -- 14. Detection of DNA damage induced by nanomaterials -- 15. Pharmacological usage of an enzyme inhibitor -- a selective inhibitor of 3-mercaptopyruvate sulfurtransferase reaction intermediate to control generation of polysulfide -- 16. Regulatory Consideration in Nanotechnology Based Drug Products. |