Biocatalysis for the pharmaceutical industry:discovery, development, and manufacturing
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Main Authors: | |
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Group Author: | ; ; |
Published: |
John Wiley & Sons Asia,
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Publisher Address: | Singapore Hoboken, NJ |
Publication Dates: | c2009. |
Literature type: | Book |
Language: | English |
Subjects: | |
Carrier Form: | x, 324 p.: ill. ; 26 cm. |
ISBN: |
9780470823149 (cloth) 0470823143 (cloth) |
Index Number: | R914 |
CLC: | R914 |
Call Number: | R914/T171 |
Contents: |
Includes bibliographical references and index. Enzymes and their synthetic applications -- Expression hosts for enzyme discovery and production -- Directed enzyme evolution and high-throughput screening -- Applications of reaction engineering to industrial biotransformations -- Chiral synthesis of pharmaceutical intermediates using oxynitrilases -- Expanding the scope of aldolases as tools for organic synthesis -- Synthetic applications of ketoreductases and alcohol oxidases -- Applications of nitrile hydratases and nitrilases -- Biosynthesis of drug metabolites -- Application of whole-cell biotransformation in the pharmaceutical industry -- Combinatorial biosynthesis of pharmaceutical natural products -- Metabolitic engineering for the development and manufacturing of pharmaceuticals -- Multimodular synthases and supporting enzymes for chemical production -- Green chemistry with biocatalysis for production of pharmaceuticals. |