Biocatalysis for the pharmaceutical industry:discovery, development, and manufacturing

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Bibliographic Details
Main Authors: Tao Junhua.
Group Author: Lin Guo-Qiang, 1943-; Liese A.; (Andreas)
Published: John Wiley & Sons Asia,
Publisher Address: Singapore Hoboken, NJ
Publication Dates: c2009.
Literature type: Book
Language: English
Subjects:
Carrier Form: x, 324 p.: ill. ; 26 cm.
ISBN: 9780470823149 (cloth)
0470823143 (cloth)
Index Number: R914
CLC: R914
Call Number: R914/T171
Contents: Includes bibliographical references and index.
Enzymes and their synthetic applications -- Expression hosts for enzyme discovery and production -- Directed enzyme evolution and high-throughput screening -- Applications of reaction engineering to industrial biotransformations -- Chiral synthesis of pharmaceutical intermediates using oxynitrilases -- Expanding the scope of aldolases as tools for organic synthesis -- Synthetic applications of ketoreductases and alcohol oxidases -- Applications of nitrile hydratases and nitrilases -- Biosynthesis of drug metabolites -- Application of whole-cell biotransformation in the pharmaceutical industry -- Combinatorial biosynthesis of pharmaceutical natural products -- Metabolitic engineering for the development and manufacturing of pharmaceuticals -- Multimodular synthases and supporting enzymes for chemical production -- Green chemistry with biocatalysis for production of pharmaceuticals.