Principles of safety pharmacology /
"This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics contain...
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Group Author: | ; |
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Published: |
Springer,
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Publisher Address: | Berlin : |
Publication Dates: | [2015] |
Literature type: | Book |
Language: | English |
Series: |
Handbook of experimental pharmacology,
volume 229 |
Subjects: | |
Summary: |
"This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constit |
Carrier Form: | viii, 481 pages : illustrations (some color) ; 25 cm. |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9783662520963 3662520966 |
Index Number: | RS380 |
CLC: | R96 |
Call Number: | R96/P957-1 |
Contents: | Part I: An overview of safety pharmacology and its role in drug discovery. A historical view and vision into the future of the field of safety pharmacology -- In vitro early safety pharmacology screening: perspectives related to cardiovascular safety -- Safety pharmacology in drug discovery and development -- Part II: The safety pharmacology core battery. CNS adverse effects: from functional observation battery/Irwin tests to electrophysiology -- Preclinical abuse potential assessment -- Overvie |