Screen LibraryPredictive toxicology : from vision to reality /
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| Group Author: | ; |
|---|---|
| Published: |
Wiley-VCH,
|
| Publisher Address: | Weinheim : |
| Publication Dates: | [2015] |
| Literature type: | Book |
| Language: | English |
| Series: |
Methods and principles in medicinal chemistry ;
volume 64 |
| Subjects: | |
| Carrier Form: | xxv, 404 pages : illustrations ; 25 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9783527336081 (hardback : alkaline paper) : 3527336087 (hardback : alkaline paper) 9783527674190 (ePDF) 9783527674206 (ePub) 9783527674213 (Mobi) 9783527674183 (oBook) |
| Index Number: | RA1211 |
| CLC: | R99 |
| Call Number: | R99/P923-1 |
| Contents: | Introduction to Predictive Toxicology Tools and Methods / Laura Suter-Dick and Friedlieb Pfannkuch -- In silico toxicology : Current Approaches and Future Perspectives to Predict Toxic Effects with Computational Tools / Thomas Steger-Hartmann -- In silico approaches: Data Management : Bioinformatics / Arnd Brandenburg, Hans Gmuender, and Timo Wittenberger -- Role of Modeling and Simulation in Toxicology Prediction / Antje-Christine Walz, Hans Peter Grimm, Christophe Meille, Antonello Caruso, Neil Parrott, and Thierry Lavé -- Genomic Applications for Assessing Toxicities of Liver and Kidney Injury / Philip Hewitt and Esther Johann -- Use of Toxicogenomics for Mechanistic Characterization of Hepatocarcinogens in Shorter Term Studies / Heidrun Ellinger-Ziegelbauer -- Discovery and Application of Novel Biomarkers / Timothy W. Gant, Emma L. Marczylo, and Martin O. Leonard -- Predictive Toxicology: Genetics, Genomics, Epigenetics, and Next-Generation Sequencing in Toxicology / Tobias Heckel and Laura Suter-Dick -- Biomarkers as Tools for Predictive Safety Assessment: Novel Markers of Drug-Induced Kidney Injury / Angela Mally -- The Use of Renal Cell Culture for Nephrotoxicity Investigations / Anja Wilmes and Paul Jennings -- The Zebrafish Model in Toxicology / Natalie Mesens -- Predictive Method Development: Challenges for Cosmetics and Genotoxicity as a Case Study / Gladys Ouédraogo, Fabrice Nesslany, Sophie Simar, Smail Talahari, Doris Lagache, Eric Vercauteren, Lauren Nakab, Astrid Mayoux, Brigitte Faquet, and Nicole Flamand -- Using Pluripotent Stem Cells and Their Progeny as an in vitro Model to Assess (Developmental) Neurotoxicity / Lisa Hoelting, Marcel Leist, and Luc Stoppini -- Stem Cell-Based Methods for Identifying Developmental Toxicity Potential / Jessica A. Palmer, Robert E. Burrier, Laura A. Egnash, and Elizabeth L.R. Donley -- Immunogenicity of Protein Therapeutics: Risk Assessment and Risk Mitigation / Harald Kropshofer -- Regulatory Aspects / Beatriz Silva Lima. |