Bacterial endotoxins /

Microbial Toxins, Volume IV: Bacterial Endotoxins covers a general introduction of bacterial endotoxins, as well as research concerning structure (both morphological and physical), chemistry, immunology, biosynthesis, and genetics of bacterial endotoxins. The book describes the general characteristi...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Kadis, Solomon; Ajl, Samuel J., 1923-; Weinbaum, G.
Published: Academic Press,
Publisher Address: New York :
Publication Dates: 1971.
Literature type: eBook
Language: English
Series: Microbial toxins ; vol. 4
Subjects:
Online Access: http://www.sciencedirect.com/science/book/9780120465040
Summary: Microbial Toxins, Volume IV: Bacterial Endotoxins covers a general introduction of bacterial endotoxins, as well as research concerning structure (both morphological and physical), chemistry, immunology, biosynthesis, and genetics of bacterial endotoxins. The book describes the general characteristics of bacterial endotoxins; the anatomy and chemistry of Gram-negative cell envelopes; and the physical structure of bacterial lipopolysaccharides. The text also discusses the isolation and chemical and immunological characterization of bacterial lipopolysaccharides; the chemistry of the unique carb.
Carrier Form: 1 online resource (473 pages) : illustrations.
Bibliography: Includes bibliographical references.
ISBN: 9781483215884
1483215881
Index Number: QP631
CLC: Q939.4
Contents: Front Cover; Bacterial Endotoxins; Copyright Page; Table of Contents; List of Contributors; Preface; Contents of Other Volumes; CHAPTER 1. General Characteristics; I. Introduction. Toward a Definition; II. Source in Cell; III. Host-Reactive Properties; IV. Physicochemical Properties; V.A Provisional Definition; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 2. The Anatomy and Chemistry of Gram-Negative Cell Envelopes; I. Anatomy of Envelopes; II. Chemistry of the Gram-Negative Cell Envelope; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 3. The Physical Structure of Bacterial Lipopolysaccharides.
I. IntroductionII. Problems in the Study of Lipopolysaccharide Structure; III. The Physical Shape of Lipopolysaccharide; IV. Determinants of Physical Shape; V. Physical Structure and Biological Function; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 4. Isolation and Chemical and Immunological Characterization of Bacterial Lipopolysaccharides; I. Introduction; II. Isolation and Properties of Lipopolysaccharides; III. Sugar Constituents and Composition of Lipopolysaccharides; IV. Structure of the O-Specific Chains and Chemical Basis of the Immunological Specificities of the O Factors.
V. Structure of Atypical Specific Chains as Found in SR and T MutantsVI. The Basal Core Structure as Provided by Analysis of R Mutant Lipopolysaccharides; VII. General Conclusions; ACKNOWLEDGMENTS; REFERENCES; CHAPTER 5. The Chemistry of the Unique Carbohydrates of Bacterial Lipopolysaccharides; I. Introduction; II. Pentoses; III. Uronic Acids; IV. Hexoses; V. Hexosamines; VI. Heptoses; VII. 6-Deoxyhexoses; VIII. 3,6-Dideoxyhexoses; IX. KDO (3-Deoxy-D-mannooctulosonic Acid, 2-Keto-3-deoxyoctonic Acid); REFERENCES.
CHAPTER 6. The Relation of Bacteriophage Attachment to Lipopolysaccharide StructureI. Introduction; II. Structure of the Gram-Negative Cell Wall; III. The Cell Wall of Enterobacteriaceae -Relationship between Antigenic Alterations and Phage Adsorption; IV. Early Work on the T Phages; V. Salmonella Phages; VI. E. coli Phages; VII. Conclusions; REFERENCES; CHAPTER 7. Chemical and Biological Heterogeneity of Endotoxins; I. Introduction; II. Morphological and Chemical Heterogeneity; III. Biological Heterogeneity; IV. Attempts to Explain the Observed Heterogeneity; V. Summary; REFERENCES.
CHAPTER 8. Biosynthesis of the Core Region of LipopolysaccharideI. Introduction; II. Pathway of Biosynthesis of the Outer Core; III. Role of Glycerophosphates in Core Glycosyl Transferase Reactions; IV. Biosynthesis of the Backbone Region; REFERENCES; CHAPTER 9. Biosynthesis of O-Antigens; I. Introduction; II. Variations in O-Antigen Structure; III. The Biosynthetic Cycle; IV. The Antigen Carrier Lipid; V. The Polymerase Reaction; VI. Transfer of O-Antigen Chains to the Lipopolysaccharide Core-The Ligase Reaction; VII. Synthesis of Other O-Antigens and Polysaccharides; REFERENCES.