Prokaryotic systems biology /

"This book focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species. The first part of the book consists of nine chapters, focusing on biochemical and genetics and genomics approaches including yeast two hybrid, metagenomics, affinit...

Full description

Saved in:
Bibliographic Details
Group Author: Krogan, Nevan J; Babu, Mohan
Published: Springer,
Publisher Address: Cham, Switzerland :
Publication Dates: [2015]
Literature type: Book
Language: English
Series: Advances in experimental medicine and biology, volume 883
Subjects:
Summary: "This book focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species. The first part of the book consists of nine chapters, focusing on biochemical and genetics and genomics approaches including yeast two hybrid, metagenomics, affinity purification in combination with mass spectrometry, chromatin-immunoprecipitation coupled with sequencing, large-scale synthetic genetic screens, and quantitative-based mass spectrometry strategies for mapping the bacterial physical, functional, substrate, and regulatory interaction networks needed f
Carrier Form: ix, 319 pages : illustrations (chiefly color) ; 25 cm.
Bibliography: Includes bibliographical references and index.
ISBN: 9783319236025
3319236024
Index Number: QH301
CLC: Q111
Call Number: Q111/P964-1
Contents: Metagenomics as a tool for enzyme discovery : hydrolytic enzymes from marine-related metagenomes -- Investigating bacterial protein synthesis using systems biology approaches -- Biology and assembly of the bacterial envelope -- Comparative genomics and evolutionary modularity of prokaryotes -- Predicting functional interactions among genes in prokaryotes by genomic context -- Functional implications for domain organization within prokaryotic rhomboid proteases -- Mapping transcription regulatory networks with ChIP-seq and RNA-seq -- Quantitative and systems-based approaches for deciphering b