Postmortem toxicology : challenges and interpretive considerations /

Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examine...

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Bibliographic Details
Main Authors: Rohrig, Timothy P. (Timothy Patrick), 1956-
Corporate Authors: Elsevier Science & Technology.
Published: Academic Press, an imprint of Elsevier,
Publisher Address: London :
Publication Dates: [2019]
©2019
Literature type: eBook
Language: English
Subjects:
Online Access: https://www.sciencedirect.com/science/book/9780128151631
Summary: Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examines pre-analytical factors, storage containers/conditions, prior medical interventions and therapy, along with information from the scene investigation and anatomical findings. This reference also provides explanation of the complicating conditions for the interpretation of the toxicological results due to postmortem decomposition, embalming artifacts and the postmortem redistribution of drugs. Tolerance is also discussed as an aid to interpreting results from a habitual/chronic user of medications and/or drugs of abuse. The book is geared towards the current practitioner; however, it is written to be used as a valuable reference for a graduate or post-graduate level courses in forensic toxicology or forensic pathology.
Carrier Form: 1 online resource : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 9780128151648
0128151641
Index Number: RA1228
CLC: D919.1
Contents: Front Cover; Postmortem Toxicology; Copyright Page; Quote; Contents; Preface; Acknowledgments; 1 Introduction; References; 2 Preanalytical Considerations; References; 3 Prior Medical Therapy and Medical Intervention; Medical Intervention; References; 4 Analytical Artifacts; References; 5 Scene Investigation; References; 6 Anatomical Findings; Intravenous Drug Administration; Mees' Lines; Foam Cone; Body Color, Lesions, and Odors; Ocular Manifestations; Oral Manifestations; Perforated Nasal Septum; Internal Examination; Lung Weight and Pulmonary Edema; Urinary Bladder Distention
Histological Examination of TissueReferences; Further Reading; 7 Unexpected Drug/Metabolites and Endogenous Compounds; References; 8 Drug Stability; References; 9 Embalming Artifacts; References; Further Reading; 10 Decomposition Products; References; 11 Postmortem Clinical Chemistries; Vitreous Fluid; Glucose; Nitrogen Compounds; Creatinine; Sodium; Chloride; Potassium; Exogenous Intoxications; Ethyl Alcohol; Synovial Fluid; Cerebrospinal Fluid; Blood; Ketoacidosis; Creatinine; Glycated Hemoglobin (HbA1c); Methemoglobin; Tryptase; References
12 Postmortem Formation of Alcohol and Other Volatile CompoundsReferences; Further Reading; 13 Postmortem Redistribution; References; 14 Interpretive Considerations of Postmortem Blood Concentrations; References; Further Reading; Appendix 1 Drug Blood to Plasma Ratios; 15 Tolerance; References; Index; Back Cover