Postmortem toxicology : challenges and interpretive considerations /
Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examine...
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Main Authors: | |
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Corporate Authors: | |
Published: |
Academic Press, an imprint of Elsevier,
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Publisher Address: | London : |
Publication Dates: |
[2019] ©2019 |
Literature type: | eBook |
Language: | English |
Subjects: | |
Online Access: |
https://www.sciencedirect.com/science/book/9780128151631 |
Summary: |
Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examines pre-analytical factors, storage containers/conditions, prior medical interventions and therapy, along with information from the scene investigation and anatomical findings. This reference also provides explanation of the complicating conditions for the interpretation of the toxicological results due to postmortem decomposition, embalming artifacts and the postmortem redistribution of drugs. Tolerance is also discussed as an aid to interpreting results from a habitual/chronic user of medications and/or drugs of abuse. The book is geared towards the current practitioner; however, it is written to be used as a valuable reference for a graduate or post-graduate level courses in forensic toxicology or forensic pathology. |
Carrier Form: | 1 online resource : illustrations |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9780128151648 0128151641 |
Index Number: | RA1228 |
CLC: | D919.1 |
Contents: |
Front Cover; Postmortem Toxicology; Copyright Page; Quote; Contents; Preface; Acknowledgments; 1 Introduction; References; 2 Preanalytical Considerations; References; 3 Prior Medical Therapy and Medical Intervention; Medical Intervention; References; 4 Analytical Artifacts; References; 5 Scene Investigation; References; 6 Anatomical Findings; Intravenous Drug Administration; Mees' Lines; Foam Cone; Body Color, Lesions, and Odors; Ocular Manifestations; Oral Manifestations; Perforated Nasal Septum; Internal Examination; Lung Weight and Pulmonary Edema; Urinary Bladder Distention Histological Examination of TissueReferences; Further Reading; 7 Unexpected Drug/Metabolites and Endogenous Compounds; References; 8 Drug Stability; References; 9 Embalming Artifacts; References; Further Reading; 10 Decomposition Products; References; 11 Postmortem Clinical Chemistries; Vitreous Fluid; Glucose; Nitrogen Compounds; Creatinine; Sodium; Chloride; Potassium; Exogenous Intoxications; Ethyl Alcohol; Synovial Fluid; Cerebrospinal Fluid; Blood; Ketoacidosis; Creatinine; Glycated Hemoglobin (HbA1c); Methemoglobin; Tryptase; References 12 Postmortem Formation of Alcohol and Other Volatile CompoundsReferences; Further Reading; 13 Postmortem Redistribution; References; 14 Interpretive Considerations of Postmortem Blood Concentrations; References; Further Reading; Appendix 1 Drug Blood to Plasma Ratios; 15 Tolerance; References; Index; Back Cover |