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Evolution of extracellular matrix /

The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical...

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Bibliographic Details
Corporate Authors: SpringerLink (Online service)
Group Author: Keeley, Fred W.; Mecham, Robert P.
Published: Springer,
Publisher Address: Berlin ; New York :
Publication Dates: ?013.
Literature type: eBook
Language: English
Series: Biology of extracellular matrix,
Subjects:
Extracellular matrix.
Evolution (Biology)
Biological Evolution.
MEDICAL > Anatomy.
SCIENCE > Human Anatomy & Physiology. > Human Anatomy & Physiology.
Life sciences.
Cytology.
Cell Biology.
Cell Physiology.
Electronic books.
Online Access: http://dx.doi.org/10.1007/978-3-642-36002-2
Summary: The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
Item Description: Includes index.
Carrier Form: 1 online resource.
ISBN: 9783642360022 (electronic bk.)
3642360025 (electronic bk.)
Index Number: QH603
CLC: Q249
Contents: Extracellular Matrix Evolution: An Overview /
Domain Shuffling and the Evolution of Vertebrate Extracellular Matrix /
Invertebrate and Vertebrate Collagens /
The Evolution of Elastin /
Evolutionary Insights into Fibrillin Structure and Function in the Extracellular Matrix /
Molecular Evolution of the Microfibril-Associated Proteins: The Fibulins and the MAGPs /
Evolution and Function of SPARC and Tenascins: Matricellular Counter-Adhesive Glycoproteins with Pleiotropic Effects on Angiogenesis and Tissue Fibrosis /
Thrombospondins and Their Receptors: Evolving Functions /
Evolution of Cell Adhesion to Extracellular Matrix /

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