Screen LibraryMetabolic engineering : principles and methodologies /
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selec...
Saved in:
| Main Authors: | |
|---|---|
| Corporate Authors: | |
| Group Author: | ; |
| Published: |
Academic Press,
|
| Publisher Address: | San Diego : |
| Publication Dates: | 1998. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780126662603 |
| Summary: |
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes. Key features of the book are pathway integr |
| Carrier Form: | 1 online resource (xxi, 725 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780080536286 008053628X |
| Index Number: | TP248 |
| CLC: | Q591-05 |
| Contents: |
The Essence of Metabolic Engineering. Review of Cellular Metabolism. Comprehensive Models for Cellular Reactions. Material Balances and Data Consistency. Regulation of Metabolic Pathways. Examples of Pathway Manipulations: Metabolic Engineering in Practice. Metabolic Pathway Synthesis. Metabolic Flux Analysis. Methods for the Experimental Determination of Metabolic Fluxes by Isotope Labeling. Applications of Metabolic Flux Analysis. Metabolic Control Analysis. Analysis of Structure of Metabolic Networks. Flux Analysis of Metabolic Networks. Thermodynamics of Cellular Processes. Glossary. Sub 1. The essence of metabolic engineering -- 2. Review of cellular metabolism -- 3. Comprehensive models for cellular reactions -- 4. Material balances and data consistency -- 5. Regulation of metabolic pathways -- 6. Examples of pathway manipulations : metabolic engineering in practice -- 7. Metabolic pathway synthesis -- 8. Metabolic flux analysis -- 9. Methods for the experimental determination of metabolic fluxes by isotope labeling -- 10. Applications of metabolic flux analysis -- 11. Metabolic control analysis -- 12. Analysis of structure of metabolic networks -- 13. Flux analysis of met |