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Xenobiotics and inflammation /

The effect of xenobiotics on general host resistance and on specific immune functions has recently become the focus of much research. Xenobiotics and Inflammation synthesizes current information on how chemicals (xenobiotics) can modulate the immune system, focusing on the process of inflammation. I...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Schook, Lawrence B.; Laskin, Debra L.
Published: Academic Press,
Publisher Address: San Diego :
Publication Dates: 1994.
Literature type: eBook
Language: English
Subjects:
Immunotoxicology.
Xenobiotics > Immunology.
Inflammation > Mediators.
Cytokines > Pathophysiology.
Growth factors > Pathophysiology.
Inflammation > immunology.
Immunotoxins.
Cytokines.
Growth Substances.
Inflammation > immunologie.
Immunotoxines.
Xe nobiotique > immunologie.
Substances de croissance.
Xenobiotica.
Ontstekingen (geneeskunde)
Entzu ndung.
Xenobiotikum.
Humans > Immunology
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780126289305
Summary: The effect of xenobiotics on general host resistance and on specific immune functions has recently become the focus of much research. Xenobiotics and Inflammation synthesizes current information on how chemicals (xenobiotics) can modulate the immune system, focusing on the process of inflammation. It provides a much needed, single-source reference for researchers investigating the mechanisms responsibIe for altered host resistance following exposure to xenobiotics.
Emphasis is on the roles of cytokines and growth factors in the inflammatory process and how production of these mediators is modified by xenobiotics. Researchers exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites will find this book timely and useful. The editors have brought together experts in inflammation, cytokines, cell growth, immunology, and toxicology to provide a highly useful volume.
Divided into three sections, the book offers an organ system approach to understanding inflammatory and xenobiotics.
Carrier Form: 1 online resource (xxi, 361 pages) : illustrations
Bibliography: Includes bibliographical references and index.
Index Number: RC582
CLC: R99
Contents: Immunotoxicity and inflammation: an overview / Gary J. Rosenthal, Michael I. Luster -- Inflammatory process / Elizabeth J. Kovacs, Michelle R. Frazier-Jessen -- Inflammatory cytokines: an overview / Mary E. Brandes, Sharon M. Wahl -- Induction of inflammation: cytokines and acute-phase proteins / C.D. Richards, J. Gauldie -- Role of tumor necrosis factor [alpha] in acute and chronic inflammatory responses: novel therapeutic approaches / Carl K. Edwards, III [and others] -- Bone marrow phagocytes, inflammatory mediators, and benzene toxicity / Laureen MacEachern, Debra L. Laskin -- Dimethylnitrosamine-associated inflammation: induction of cytokines affecting macrophage differentiation and functions / Lawrence B. Schook [and others] -- Effects of metals on lymphocyte development and function / Michael J. McCabe, Jr., David A. Lawrence -- Xenobiotic-induced skin toxicity / Jeffrey D. Laskin, Diane E. Heck -- Pathogenesis of atherosclerosis: a cytokine hypothesis / George Ku, Richard L. Jackson -- Ozone-induced inflammatory response in pulmonary cells / Hillel S. Koren, Robert B. Devlin, Susanne Becker.
(cont) Pulmonary fibrosis induced by silica, asbestos and bleomycin / Pierre F. Piguet -- Nonparenchymal cells, inflammatory mediators and hepatotoxicity / Debra L. Laskin -- Central nervous system: viral infection and immune-mediated inflammation / Georgia Schuller-Levis, Piotr B. Kozlowski, Richard J. Kascsak.

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