Screen LibraryIntracranial aneurysms /
Intracranial aneurysm result from complex interactions between cerebrovascular anatomy, vascular injury, and adaptive remodeling of the arterial wall and represent a cerebrovascular disorder with the potential for substantial morbidity and mortality. Most intracranial aneurysms occur in the larger a...
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| Published: |
Academic Press, An imprint of Elsevier,
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| Publisher Address: | London : |
| Publication Dates: | [2018] |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
https://www.sciencedirect.com/science/book/9780128117408 |
| Summary: |
Intracranial aneurysm result from complex interactions between cerebrovascular anatomy, vascular injury, and adaptive remodeling of the arterial wall and represent a cerebrovascular disorder with the potential for substantial morbidity and mortality. Most intracranial aneurysms occur in the larger arteries near the skull base, in or around the circle of Willis, but variants may appear virtually anywhere in the cerebral vasculature. The aneurysm can leak or rupture, causing life-threatening bleeding, and is the most common cause of spontaneous subarachnoid hemorrhage, the third most common form of stroke. Intracranial aneurysms affect about 1 in 10,000 people per year in the United States (approximately 27,000). Intracranial Aneurysms will address the natural history, biology, and basic management principles and treatment of aneurysms. The chapters also explore the unique features of each type or location of aneurysm while considering the medical, surgical, and endovascular options. Contributions are by members of the Endovascular Neurosurgery Research Group, a group of recognized expert neurosurgeons who specialize in cerebrovascular and endovascular management of aneurysms. |
| Carrier Form: | 1 online resource (xxii, 714 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780128118832 0128118830 |
| Index Number: | RC693 |
| CLC: | R739.41 |
| Contents: |
Front Cover; Intracranial Aneurysms; Copyright; Contents; Contributors; Preface; Reference; Companion Web Site; Acknowledgments; Part I: Background; Chapter 1: Cerebrovascular Embryology and Implications for the Pathogenesis of Cerebral Aneurysms; 1.1. Vasculogenesis and Angiogenesis; 1.1.1. Vasculogenesis; 1.1.2. Angiogenesis; 1.2. Embryology of the Cerebral Arterial Circulation; 1.2.1. Origins of the Embryonic Circulatory System; 1.2.2. Development of the Carotid Circulation; 1.2.3. Development of the Vertebrobasilar Circulation; 1.3. Mural Structure of Cerebral Arteries 1.4. Cerebral Arterial Bifurcations as an Anatomical Vulnerability1.5. Anatomical Variants of Persistent Fetal Circulation (Fig. 1.2); 1.5.1. Fetal PCA; 1.5.2. Primitive Carotid-Vertebrobasilar Anastomoses; 1.5.3. Persistent Trigeminal Artery; 1.5.4. Persistent Otic Artery; 1.5.5. Persistent Hypoglossal Artery; 1.5.6. Proatlantal Intersegmental Artery; 1.5.7. Congenital Absence of the ICA; 1.5.7.1. Arterial Fenestrations; 1.6. Conclusions; References; Chapter 2: Biology of Cerebral Aneurysm Formation, Growth, and Rupture; 2.1. Introduction; 2.2. Formation of Intracranial Aneurysms 2.2.1. Epidemiological Risk Factors2.2.2. Genetic Factors; 2.2.3. Structural and Molecular Changes; 2.3. Atherosclerosis and Saccular Intracranial Aneurysms; 2.4. Hemodynamics and Biology; 2.5. Aneurysm Growth; 2.6. Aneurysm Wall Inflammation; 2.7. Aneurysm Rupture; 2.7.1. Risk Factors for Aneurysm Rupture; 2.7.2. Patient-Related Risk Factors; 2.7.3. Aneurysm-Related Risk Factors; 2.7.4. Triggers of Aneurysm Rupture; References; Chapter 3: Experimental Aneurysm Models; 3.1. Concepts for Models; 3.1.1. Selection of an Animal Species; 3.1.2. The ``Ideal Model; 3.1.3. Histology of Aneurysms 3.2. Early Models and History3.3. Classification of Models; 3.3.1. Rabbit Elastase Model; 3.3.2. Surgical Models; 3.3.2.1. Animal Selection; 3.3.2.2. Types of Anastomosis (Fig. 3.3); 3.3.2.3. General Principles of Surgical Technique; 3.3.2.4. Complications; 3.3.2.5. Other Technical Considerations; 3.3.3. Bifurcation Models; 3.3.3.1. A Bifurcation Aneurysm Model for the Future; 3.3.4. Murine Models; 3.3.4.1. Mouse Intracranial Elastase Model; 3.3.4.2. Hashimoto Model-Renal Hypertension and Lathyrism; 3.3.4.3. Ovarectomized Rat Model; 3.4. Special Aneurysm Models; 3.4.1. Aneurysms With No Neck 3.4.2. FD in Aneurysm Models3.5. Limitations of Current Models; 3.6. Conclusion; References; Chapter 4: Training Standards in Neuroendovascular Surgery (NES); 4.1. Introduction; 4.2. Background; 4.3. Prerequisite Training (Reprinted with permission from Stroke 48, 2017, 2328-2325); 4.3.1. Neurosurgeons; 4.3.2. Neurologists; 4.3.3. Radiologists; 4.4. Program Requirements (Reprinted with permission from Stroke 48, 2017, 2328-2325); 4.5. Program Personnel and Resources (Reprinted with permission from Stroke 48, 2017, 2328-2325) |