Screen LibraryEnvironmental factors in neurodevelopmental and neurodegenerative disorders /
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Academic Press : Elsevier,
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| Publisher Address: | Amsterdam : |
| Publication Dates: |
[2015] ©2015 |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780128002285 |
| Summary: |
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with. |
| Carrier Form: | 1 online resource |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780128004074 012800407X |
| Index Number: | QP363 |
| CLC: | Q42 |
| Contents: |
Front Cover; Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders; Copyright; Contents; Preface; Foreword; Contributors; Section-01 -- Neurodevelopmental Disorders ; CHAPTER 1 -- OVERVIEW OF THE ROLE OF ENVIRONMENTAL FACTORS IN NEURODEVELOPMENTAL DISORDERS; INTRODUCTION; EVIDENCE IMPLICATING ENVIRONMENTAL FACTORS; FOR NEURODEVELOPMENTAL DISORDERS; MECHANISMS BY WHICH ENVIRONMENTAL FACTORS INFLUENCE RISK OF NEURODEVELOPMENTAL DISORDERS; CONCLUSIONS; References; Chapter 2 -- Genetic Factors in Environmentally Induced Disease; INTRODUCTION; PARKINSON'S DISEASE AMYOTROPHIC LATERAL SCLEROSISALZHEIMER'S DISEASE; CONCLUSIONS AND FUTURE DIRECTIONS; References; Chapter 3 -- Fetal Alcohol Spectrum Disorders: Effects and Mechanisms of Ethanol on the Developing Brain; INTRODUCTION; FETAL ALCOHOL SPECTRUM DISORDERS (FASD); FASD PREVALENCE; NEUROBEHAVIORAL DEFICITS IN FASD; FASD AND BRAIN STRUCTURES; ANIMAL MODELS FOR FASD; MECHANISMS INVOLVED IN FASD; EXPERIMENTAL TREATMENTS FOR FASD; Acknowledgments; References; Chapter 4 -- Prenatal Infection: Setting the Course of Brain Aging and Alzheimer's Disease?; INTRODUCTION; WHAT CHARACTERIZES ALZHEIMER'S DISEASE? ALZHEIMER'S DISEASEBASIC CELLULAR FUNCTIONS; FROM AXONAL VARICOSITIES TO AXONAL DEGENERATION; CONCLUSIONS; References; Chapter 5 -- Neurobehavioral Effects of Air Pollution in Children; INTRODUCTION; EVIDENCE FROM EPIDEMIOLOGICAL RESEARCH; EVIDENCE FROM ANIMAL RESEARCH; BIOLOGICAL PATHWAYS; EVALUATION OF THE EVIDENCE AND FUTURE RESEARCH DIRECTIONS; CONCLUSIONS; References; Chapter 6 -- The Role of Methylmercury Exposure in Neurodevelopmental and Neurodegenerative Disorders; INTRODUCTION; FETAL MINAMATA DISEASE AND ASSOCIATED DISORDERS Environmental epidemiology studies of low-level mehg exposure: improving measurements and methodsof maternal fish consumption for childhood outcomes; insights on neurobehavioral effects of mehg from animal model studies; cross-species comparisons of mehg neurodevelopmental effects; mechanisms underlying mehg-mediated neurotoxicity; energetics, altered ca2+ homeostasis, and production of reactive oxygen species; effects of mehg on microtubules as a mechanism underlying developmental neuropathology; effects of mehg on astrocytes and microglia; neuronal signaling DELAYED NEUROTOXICITY, NEURODEGENERATIVE DISEASE, AND INTERGENERATIONAL EFFECTSTHE SOCIETAL AND HUMAN COSTS OF MEHG EXPOSURE; Acknowledgments; References; Chapter 7 -- Developmental Exposure to Lead: Overview and Integration of Neurobehavioral Consequences and Mediation; INTRODUCTION AND FOCUS; AND OCCUPATIONAL CONTAMINANT; THE PERSISTENT QUESTION OF WHETHER ELEVATED LEAD EXPOSURE REDUCES IQ; CHANGES IN LEARNING; AS BEHAVIORAL MECHANISMS OF LEAD-INDUCED LEARNING AND IQ DEFICITS?; PERSISTENCE OF DEVELOPMENTAL LEAD NEUROTOXICITY |