Screen LibraryLead generation approaches in drug discovery
An integrated overview of modern approaches to lead discovery. Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to im...
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| Group Author: | ; |
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| Literature type: | Electronic eBook |
| Language: | English |
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| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9780470584170 |
| Summary: |
An integrated overview of modern approaches to lead discovery. Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Drug Discove |
| Carrier Form: | 1 online resource (xi, 295 p.) : ill. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780470584170 0470584173 9780470584163 (electronic bk.) 0470584165 (electronic bk.) |
| Index Number: | RM301 |
| CLC: | R914 |
| Contents: | Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith - |