Adenosine receptors and Parkinson's disease /

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. Thi...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology
Group Author: Kase, Hiroshi; Richardson, Peter J; Jenner, Peter, 1946
Published: Academic Press,
Publisher Address: San Diego, CA :
Publication Dates: 2000.
Literature type: eBook
Language: English
Series: Pure and applied mathematics series ; v. 90
Subjects:
Online Access: http://www.sciencedirect.com/science/book/9780124004054
Summary: This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Key Features * Discusses the discovery and development of a novel non-dopaminomim
Carrier Form: 1 online resource (xviii, 275 pages [1] color plate) : illustrations.
Bibliography: Includes bibliographical references and index.
ISBN: 9780124004054
0124004059
9781435605138
1435605136
0080525954
9780080525952
128105383X
9781281053831
Index Number: RC382
CLC: R742.5
Contents: Introductory Remarks: Adenosine A2A Receptor Antagonists: A Novel Approach to the Treatment of Parkinson's Disease. /
Localisation of Adenosine Receptors in Brain and Periphery. /
Medicinal Chemistry of Adenosine Receptors in Brain and Periphery. /
Overview of the Physiology and Pharmacology of Adenosine in the Peripheral System. /
Biochemical Characterization of Adenosine Agonists and Antagonists. /
Physiology of Adenosine Receptors in the Striatum: Reg