Cancer risk assessment chemical carcinogenesis, hazard evaluation, and risk quantification /

"With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, m...

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Bibliographic Details
Group Author: Hsu, Ching-Hung.; Stedeford, Todd.
Published:
Literature type: Electronic eBook
Language: English
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9780470622728
Summary: "With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous"--Provided by publisher.
Carrier Form: 1 online resource (xxxi, 824 p., [8] p. of plates) : ill. (some col.)
Bibliography: Includes bibliographical references and index.
ISBN: 9780470622711 (electronic bk.)
0470622717 (electronic bk.)
9780470622728 (online lib.)
0470622725 (online lib.)
1282683357
9781282683358
Index Number: RC268
CLC: R730.231
Contents: CANCER RISK ASSESSMENT: Chemical Carcinogenesis, Hazard Evaluation, and Risk Quantification; CONTENTS; PREFACE; CONTRIBUTORS; ABBREVIATIONS AND ACRONYMS; PART I: CANCER RISK ASSESSMENT, SCIENCE POLICY, AND REGULATORY FRAMEWORKS; CHAPTER 1: CANCER RISK ASSESSMENT; CHAPTER 2: SCIENCE POLICY AND CANCER RISK ASSESSMENT; CHAPTER 3: HAZARD AND RISK ASSESSMENT OF CHEMICAL CARCINOGENICITY WITHIN A REGULATORY CONTEXT; CHAPTER 4: USE OF CANCER RISK ASSESSMENTS IN DETERMINATION OF REGULATORY STANDARDS; PART II: CANCER BIOLOGY AND TOXICOLOGY; CHAPTER 5: THE INTERPLAY OF CANCER AND BIOLOGY.
Chapter 6: chemical carcinogenesis: a brief history of its concepts with a focus on polycyclic aromatic hydrocarbonschapter 7: hormesis and cancer risks: issues and resolution; chapter 8: thresholds for genotoxic carcinogens: evidence from mechanism-based carcinogenicity studies; part iii: genetic toxicology, testing guidelines and regulations, and novel assays; chapter 9: development of genetic toxicology testing and its in.