Molecular and cellular aspects of the serpinopathies and disorders in serpin activity /

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Bibliographic Details
Corporate Authors: World Scientific Firm
Group Author: Silverman, Gary A., 1955; Lomas, David A
Published: World Scientific,
Publisher Address: Singapore ; Hackensack, N.J. :
Publication Dates: 2007.
Literature type: eBook
Language: English
Subjects:
Online Access: http://www.worldscientific.com/worldscibooks/10.1142/6215#t=toc
Carrier Form: 1 online resource (xxix,639pages) : illustrations (some color)
Bibliography: Includes bibliographical references and index.
ISBN: 9812707549 (electronic bk.)
9789812707543 (electronic bk.)
CLC: Q51
Contents: Section I. Overview of the serpin superfamily.
Section II. Lessons from model organisms.
Section III. Serpin physiology and patholophysiology.
Section IV. Congenital deficiencies and serpinopathies.
Evolution and classification of the serpin superfamily /
Serpin conformations /
Mechanisms of Serpin inhibition /
Mouse serpins and transgenic studies /
Serpins in prokaryotes /
New Lessons from poxvirus serpins /
The intracellular serpins of caenorhabditis elegans /
Drosophila serpins: regulatory cascades in innate immunity and morphogenesis /
Serpins in a lepidopteran insect, manduca sexta /
MENT, a chromatin-associated serpin from Avia
Serpins, apoptosis and other aspects of cell death /
Serpins in malignancy: tumor cell invasion, motility and angiogenesis /
Serpins in malignancy: prognostic indicators /
SERPINB7 (Megsin) nephropathy /
Serpin-protein and receptor interactions /
Serpins and the metabolic syndrome /
Serpin interactions with bacterial peptidases /
The serpinopathies and respiratory disease /
Liver disease in 1-Antitrypsin deficiency /
Regulation of hmostasis by Heparin-binding serpins /
C1 inhibitor: structure, function, biologic activity and angioedema /
Neuroserpin in neurological disease /
Serpins and Alzheimer's disease /