Screen LibraryNovel therapeutic targets for antiarrhythmic drugs
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| Group Author: | |
|---|---|
| Published: |
John Wiley & Sons,
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| Publisher Address: | Hoboken, N.J. |
| Publication Dates: | c2010. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xxiv, 578 p., [8] p. of plates: ill. (some col.) ; 25 cm. |
| ISBN: |
9780470261002 (cloth) 0470261005 (cloth) |
| Index Number: | R541 |
| CLC: |
R541.7 R972 |
| Call Number: | R541.7/N937 |
| Contents: |
Includes bibliographical references and indexes. Myocardial K+ channels : primary determinants of action potential repolarization / Noriko Niwa and Jeanne Nerbonne -- The "funny" pacemaker current / Andrea Barbuti ... [et al.] -- Arrhythmia mechanisms in ischemia and infarction / Ruben Coronel ... [et al.] -- Antiarrhythmic drug classification / Cynthia A. Carnes -- Repolarization reserve and proarrhythmic risk / András Varró -- Safety challenges in the development of novel antiarrhythmic drugs / Gary Gintant and Zhi Su -- Safety pharmacology and regulatory issues in the development of antiarrhythmic medications / Armando Lagrutta and Joseph J. Salata -- Ion channel remodeling and arrhythmias / Takeshi Aiba and Gordon F. Tomaselli -- Redox modification of ryanodine receptors by heart failure and cardiac arrhythmias and failure : a potential therapeutic target / Andriy E. Belevych, Dmitry Terentyev, and Sandor Györke -- Targeting Na+/CA²+ exchange as an antiarrhythmic strategy / Gundrun Antoons, Rik Willems, and Karin R. Sipido -- Calcium/calmodulin-dependent protein kinase II (CaMKII) : modulation of ion currents and potential role for arrhythmias / Lars S. Maier -- Selective targeting of ventricular potassium channels for arrhythmia suppression : feasible or risible? / Hugh Clements-Jewery and Michael Curtis -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists : a class of drugs that may selectively target the ischemic myocardium / George E. Billman -- Mitochondrial origin of ischemia-reperfusion arrhythmias / Brian O'Rourke -- Cardiac gap junctions : a new target for antiarrhythmic drugs : gap junction modulators / Anja Hagen and Stefan Dhein -- Novel pharmacological targets for the management of atrial fibrillation / Alexander Burashnikov and Charles Antzelevitch -- IKur, ultra-rapid delayed rectifier potassium current : a therapeutic target for atrial arrhythmias / Arun Sridhar and Cynthia A. Carnes -- Non-pharmacologic manipulation of the autonomic nervous system in human for the prevention of life-threatening arrhythmias / Peter J. Schwartz -- Effects of endurance exercise training on cardiac autonomic regulation and susceptibility to sudden cardiac death : a nonpharmacological approach for the prevention of ventricular fibrillation / George E. Billman -- Dietary omega-3 fatty acids as a nonpharmacological antiarrhythmic intervention / Barry London and J. Michael Frangiskakis. |