Neurogenic inflammation in health and disease /

Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Jancso , Ga bor. (Editor)
Published: Elsevier,
Publisher Address: Amsterdam ; London :
Publication Dates: 2009.
Literature type: eBook
Language: English
Edition: First edition.
Series: Neuroimmune biology, v. 8
Subjects:
Online Access: http://www.sciencedirect.com/science/bookseries/15677443/8
Summary: Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain.
Carrier Form: 1 online resource (xix, 346 pages, [4] pages of plates) : illustrations (some color).
Bibliography: Includes bibliographical references and index.
ISBN: 9780080932620
0080932622
Index Number: RB131
CLC: R364.5
Contents: Sensory nerves as modulators of cutaneous inflammatory reactions in health and disease / Ga bor Jansco [and others] -- The nature of electrophysiological properties of the afferent neurons involved in neurogenic inflammation in the skin / Bruce Lynn -- Peptidergic innervation of blood vessels / Thomas M. Scott, Michael M. Scott -- Molecular mechanisms of TRPV1-mediated pain / Istvan Nagy, Cleoper C. Paule, John P.M. White -- The role of the vanilloid and related receptors in nociceptor function and neuroimmune regulation / Daniel N. Cortright, Arpad Szallasi -- Somatostatin as an anti-inflammatory neuropeptide : from physiological basis to drug development / Erika Pinte r [and others] -- Effects of bradykinin on nociceptors / Ga bor Petho , Peter W. Reeh -- The inhibition of neurogenic inflammation / Josef Donnerer, Ulrike Holzer-Petsche -- Neurogenic vascular responses in the dura mater and their relevance for the pathophysiology of headaches / Ma ria Dux, Karl Messlinger -- Neurogenic mechanisms in arthritis / Lucy F. Donaldson -- Neurogenic regulation of bradykinin-induced synovitis / Paul G. Green -- Capsaicin-sensitive sensory nerves in myocardial ischemia-reperfusion injury and ischemic stress adaptation : role of nitric oxide and calcitonin gene-related peptide / Pe ter Ferdinandy, Ga bor Jansco -- Tachykinins and neurogenic inflammation at visceral level / Riccardo Patacchini, Carlo A. Maggi -- The role of the vagus nerve in afferent signaling and homeostasis during visceral inflammation / Peter Holzer.