Using animal models in biomedical research : a primer for the investigator /

Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials....

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Bibliographic Details
Corporate Authors: World Scientific Firm
Group Author: Chow, Pierce K. H; Ng, Robert T. H; Ogden, Bryan E
Published: World Scientific Pub. Co.,
Publisher Address: Singapore :
Publication Dates: 2007.
Literature type: eBook
Language: English
Subjects:
Online Access: http://www.worldscientific.com/worldscibooks/10.1142/6454#t=toc
Summary: Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. Such in vivo modes are especially important in proof-of-principle experiments and in establishing the preclinical safety and efficacy data required for progressing to human clinical trials. A practical understanding of the choice, care and use of animal models is thus expected and required of all biomedical researchers. However, while both legislations and the practice of laboratory animal science have made great advances in the last decade and have impacted significantly on the use
Carrier Form: 1 online resource (xviii,290pages) : illustrations (some color)
Bibliography: Includes bibliographical references (pages 281-285) and index.
ISBN: 9812812024 (electronic bk.)
9789812812025 (electronic bk.)
CLC: R-332
Contents: ch. 1. Scientific considerations and choice of species. ch. 1.1. The rationale for the use of animal models in biomedical research / Pierce Chow. ch. 1.2. Experimental animal models in biomedical resarch / Robert Ng. ch. 1.3. Nonhuman primates as models in biomedical research / Jason Vilano and Bryan Ogden -- ch. 2. Regulatory considerations in the use of animal models. ch. 2.1. Laws, regulations and guidelines for biomedical research in Singapore / Boon Theng Kuah. ch. 2.2. The functions of the institutional animal care and use committee / Pierce Chow. ch. 2.3. Responsibilities of principal