Chikungunya virus : advances in biology, pathogenesis, and treatment /
The mosquito-transmitted Chikungunya virus (CHIKV) is associated with increased morbidity and debilitating chronic musculoskeletal disease in infected humans. Aedes mosquitoes, responsible for CHIKV transmission, were previously restricted to the tropical and subtropical regions of the world but inc...
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Group Author: | |
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Published: |
Springer,
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Publisher Address: | Cham : |
Publication Dates: | [2016] |
Literature type: | Book |
Language: | English |
Subjects: | |
Summary: |
The mosquito-transmitted Chikungunya virus (CHIKV) is associated with increased morbidity and debilitating chronic musculoskeletal disease in infected humans. Aedes mosquitoes, responsible for CHIKV transmission, were previously restricted to the tropical and subtropical regions of the world but increased globalization has resulted in their worldwide spread. Currently, however, there are no vaccines or effective therapies for CHIKV infection, leaving infected people to rely on their immune system to fight the disease. Chikungunya Virus: Advances in Biology, Pathogenesis, and Treatment details the exciting discoveries that have been made in various aspects of CHIKV research, including: · epidemiology · biology · mechanisms of infection and pathogenesis · host response to infection · clinical syndromes and therapy Written by leading experts, the book provides a unique resource on CHIKV, intended for researchers, clinicians, educators, public health officials, and the general public. |
Carrier Form: | x, 197 pages : illustrations (some color), forms ; 24 cm |
Bibliography: | Includes bibliographical references. |
ISBN: |
9783319429564 (hardback : alkaline paper) : 3319429566 (hardback : alkaline paper) 9783319429588 (eBook) 3319429582 (eBook) |
Index Number: | RC124 |
CLC: | R373.9 |
Call Number: | R373.9/C534 |
Contents: | Clinical syndrome and Therapy / Sylvie Abel and André Cabié -- Host response and mechanisms of subversion of chikungunya / Lisa F.P. Ng and Pierre Roques -- Epidemiological history of chikungunya virus / Ann M. Powers -- Vaccines against chikungunya virus infection / Karl Ljungberg, Beate M. Kümmerer, Pierre Roques, Mariano Esteban, Andres Merits, and Peter Liljeström -- Function of chikungunya virus structural proteins / Stefan W. Metz and Gorben P. Pijlman -- Functions of chikungunya virus nonstructural proteins / Tero Ahola and Andres Merits -- Interaction of chikungunya virus with the mosquito vector / Konstantin Tsetsarkin, Lark L. Coffey, and Scott C. Weaver -- Chikungunya virus entry and replication / Nathalie Chazal and Laurence Briant -- Chikungunya virus-induced autophagy and apoptosis / Delphine Judith, Thérèse Couderc, and Marc Lecuit -- Chikungunya virus pathogenesis / David W. Hawman and Thomas E. Morrison -- Restriction factors and chikungunya virus / Wadie D. Mahauad-Fernandez and Chioma M. Okeoma. |