Screen LibraryTranslational research in genetics and genomics
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| Main Authors: | |
|---|---|
| Published: |
Oxford University Press,
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| Publisher Address: | Oxford New York |
| Publication Dates: | 2008. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xiv, 220 p.: ill. ; 25 cm. |
| ISBN: |
9780195313765 (alk. paper) 0195313763 (alk. paper) |
| Index Number: | Q3 |
| CLC: |
Q3 R394 |
| Call Number: | R394/S655 |
| Contents: |
Includes bibliographical references (p. 179-206) and index. Isolation of disease genes through genomics -- Advances in genome analysis : discovery of structural variation and genomic dosage differences in health and disease -- Significance of DNA sequence changes for diagnosis and therapy -- Epigenetics -- Complex diseases : molecular genetic contributions to elucidation of etiopathogenesis of late-onset neurodegenerative diseases -- Advances in treatment of single gene disorders through translational science : treatment with small molecules (chaperones), and gene-based therapies -- From gene discovery in genetic syndromes to identification of therapeutic agents -- Impact of the environment on the genome -- Molecular defects in cancer : application to therapy -- Pharmacogenetics and pharmacogenomics -- Phenomes, phenotypes, and clinical genetic services. |