The biology of mRNA : structure and function /

The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting...

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Bibliographic Details
Group Author: Oeffinger, Marlene; Zenklusen, Daniel
Published: Springer,
Publisher Address: Cham :
Publication Dates: [2019]
Literature type: Book
Language: English
Series: Advances in Experimental Medicine and Biology, volume 1203
Subjects:
Summary: The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. This book shows how new technologies have led to a better understanding of these processes and their connected diseases. The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regula
Carrier Form: viii, 312 pages : illustrations (some color), forms ; 25 cm.
Bibliography: Includes bibliographical references.
ISBN: 9783030314330 (hardback) :
3030314332 (hardback)
Index Number: QH506
CLC: Q786
Call Number: Q786/B615
Contents: Regulation of co-transcriptional mRNP assembly -- mRNA export through the NPC -- Roles of mRNA modifications in gene regulation -- Studying mRNPs using single molecule approaches -- Difference between mRNPs and lncRNAs? -- RNPs and/or sequence motives in mRNA localization -- mRNP structure -- New RNA binding proteins: mRNP composition -- Aggregation of repeats RNAs in neurodegenerative diseases -- mRNA structural organization and translation -- How to decide to make an mRNA -- degradation -- Methods to study mRNP composition -- mRNA-DNA kisses -- R-loops -- Forms of mRNA editing and their ro