Screen LibraryIdiotypes in medicine : autoimmunity, infection, and cancer /
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing ant...
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| Corporate Authors: | |
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| Group Author: | ; ; |
| Published: |
Elsevier,
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| Publisher Address: | Amsterdam ; New York : |
| Publication Dates: | 1997. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780444828071 |
| Summary: |
This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines. |
| Carrier Form: | 1 online resource (xv, 540 pages) : illustrations (some color) |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780444828071 0444828079 9780080534435 0080534430 1281060003 9781281060006 |
| Index Number: | QR186 |
| CLC: | R392.11 |
| Contents: | General Section -- Chapter 1. Anti-idiotypes as Vaccines: Theoretical Considerations -- Chapter 2. Anti-idiotypes -- Chapter 3. X-ray Crystallographic Studies of the Idiotypic Cascade -- Chapter 4. The Structure and Thermodynamics of Antibody-Protein Antigen Interactions -- Autoimmunity Section -- Chapter 5. Introduction -Idiotypes and Anti-idiotypes -- Chapter 6. Cross-Reactive Idiotypes in Human Lupus Families -- Chapter 7. Idiotypes of Anti-DNA Antibodies -- Chapter 8. Idiotypes of Anti-Sm Antibodies -- Chapter 9. Idiotypes of Anti-Ro and Anti-La -- Chapter 10. Idiotypes on Autoantibodies in Myasthenia Gravis -- Chapter 11. Idiotypes of ANCA -- Chapter 12. Ig Genes and Idiotype of Anti-Mitochondria1 Antibodies in Primary Biliary Cirrhosis -- Chapter 13. Idiotypes of Anti-Phospholipid Antibodies -- Chapter 14. Anti-Idiotypic Antibodies Against Human Insulin Autoantibodies (IAA) -- Chapter 15. Molecular and Cellular Aspects of Human Rheumatoid Factor Production and Idiotypes -- Chapter 16. Idiotypes of Anti-Thyroglobulin Antibodies -- Chapter 17. Idiotypes of Human Platelet-Specific Antibodies -- Chapter 18. Idiotypes of Platelet Associated Antibodies (Autoimmune Thrombocytopenia) -- Chapter 19. Idiotypes of Natural Autoantobodies and Monoclonal Gammopathies -- Chapter 20. Idiotypes and Anti-Idiotypes in Allergy -- Chapter 21. Anti-idiotypes to Autoantibodies in Therapeutic Preparations of Normal Polyspecific Human IgG (Intravenous Immunoglobulin, IVIg) -- Chapter 22. Manipulation of Autoantibody Idiotypes In Autoimmune Diseases -- Chapter 23. Anti-Idiotypic Monoclonal Antibody (mAb) to Anti-CD4 mAb as Surrogate of Human CD4 Antigen (Ag) for Active Immunotherapy of Autoimmune Diseases -- Infection Section -- Chapter 24. Introduction -- Chapter 25. Anti-Idiotypic Studies of the Glycoprotine B (gB, UL55) Complex of Human Cytomegalovirus: Mimicry of a Neutralizing Epitope and Development of Diagnostics -- Chapter 26. Anti-Idiotype Antibody in HIV- l-Infected Thrombocytopenic Patients -- Chapter 27. An Electron Microscopic View of the Geometry and Dynamics of Idiotype-Anti-Idiotype Interactions -- Chapter 28. Probing Human Antibody Diversity in HIV Infection -- Chapter 29. Anti-Idiotype Mimics of Pseudomonas Aeruginosa Surface Polysaccharides -- Chapter 30. Modulation of the Immune Response to Simian Virus 40 Large Tumor Antigen via Idiotype-Anti-Idiotype Interactions -- Chapter 31. The Perpetual Network Theory and its Putative Applications: 21 Years Later -- Chapter 32. An Anti-Idiotypic Antibody as a Functional Mirror Image of a Viral Antigen -- Chapter 33. Anti-Idiotype to Bluetongue Virus VP7 Antigen: Potential Diagnostic Reagent and Vaccine -- Chapter 34. An Idiotype Vaccine Against Gram-Negative Bacterial Sepsis -- Chapter 35. Yeast Killer Toxin-Like Antibodies in Experimental and Clinical Candidasis -- Chapter 36. Anti-Idiotypic Antibodies and Idiotypic T Cell Selection in HIV Infection -- Chapter 37. Probing Human Polysaccharide-Specific Antibody Repertoires using Anti-Idiotypes -- Chapter 38. Anti-Idiotypic Antibodies in HIV-Infected Patients to a Neutralizing Mab and its Complementarity determining regions -- Chapter 39. Epstein-Barr Virus-Induced Autoimmunity Through Anti-Idiotype Studies -- Cancer Section -- Chapter 40. Introduction -- Chapter 41. Cancer Therapy with Anti-Idiotypic Antibodies -- Chapter 42. Immunotherapy of Cancer Patients with Anti-Idiotype Vaccines -- Chapter 43. Anti-Idiotype Antibodies Mimicking Carcinoembryonic Antigen -- Chapter 44. Immunological and Molecular Characterization of an Idiotypic Cascade Specific for the Human Carcinoembryonic Antigen -- Chapter 45. Anti-Idiotypic Antibodies that Mimic the Colorectal Cancer Antigen CO17- lA/GA733: Twelve Years of Pre-Clinical and Clinical Studies -- Chapter 46. Idiotypic Network Responses and Anti-Idiotypes in Cancer Therapy -- Chapter 47. Anti-Idiotypes in Ovarian Cancer -- Chapter 48. Anti-Idiotype Antibodies in Renal Cell Carcinoma -- Chapter 49. Clinical Studies with Anti-Idiotypic Monoclonal Antibody BEC2 that Mimics GD3 Ganglioside -- Chapter 50. The Anti-Idiotypic Approach to Active Specific Immunotherapy of Malignant Melanoma. |