Nonclinical drug administration : formulations, routes and regimens for solving drug delivery problems in animal model systems /

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Bibliographic Details
Main Authors: Gad, Shayne C., 1948
Group Author: Spainhour, Charles B
Published: CRC Press,
Publisher Address: Boca Raton, FL :
Publication Dates: [2018]
Literature type: Book
Language: English
Subjects:
Carrier Form: xiv, 406 pages : tables ; 25 cm
Bibliography: Includes bibliographical references and index.
ISBN: 9781466502536
1466502533
Index Number: RS420
CLC: R914.2
Call Number: R914.2/G123
Contents: Pharmacotherapy, toxicodynamics, and regulatory science : divergent objectives -- Nonclinical pharmacokinetics : a primer -- Routes of administration : with considerations for species specificity -- Delivery systems -- Regimens (bolus/infusion, once a day/BID/TID) -- The utility of circadian oscillations in formulation and drug development -- Fundamentals of nonclinical formulation : chemistry and biological behavior -- Excipients and vehicles : tolerance and toxicity (including species specificity) -- Novel ways of improving regional and selective delivery.