Nonclinical drug administration : formulations, routes and regimens for solving drug delivery problems in animal model systems /
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Main Authors: | |
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Group Author: | |
Published: |
CRC Press,
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Publisher Address: | Boca Raton, FL : |
Publication Dates: | [2018] |
Literature type: | Book |
Language: | English |
Subjects: | |
Carrier Form: | xiv, 406 pages : tables ; 25 cm |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9781466502536 1466502533 |
Index Number: | RS420 |
CLC: | R914.2 |
Call Number: | R914.2/G123 |
Contents: | Pharmacotherapy, toxicodynamics, and regulatory science : divergent objectives -- Nonclinical pharmacokinetics : a primer -- Routes of administration : with considerations for species specificity -- Delivery systems -- Regimens (bolus/infusion, once a day/BID/TID) -- The utility of circadian oscillations in formulation and drug development -- Fundamentals of nonclinical formulation : chemistry and biological behavior -- Excipients and vehicles : tolerance and toxicity (including species specificity) -- Novel ways of improving regional and selective delivery. |