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Protein targeting, transport & translocation /

This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Dalbey, Ross E. (Editor); Heijne, Gunnar von. (Editor)
Published: Academic Press,
Publisher Address: Amsterdam ; San Diego, CA :
Publication Dates: 2002.
Literature type: eBook
Language: English
Subjects:
Proteins > Physiological transport.
Protein Transport.
Prote ines > Transport physiologique.
SCIENCE > Biochemistry. > Biochemistry.
Eiwitten.
Biologisch transport.
Translocatie.
Drug targeting.
Membranen.
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780122007316
Summary: This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. Key Features * Basic principles and techniques * Targeting and sorting sequences * Protein export in bacteria * Membrane protein integration into ER and bacterial membranes * Protein translocation across the ER * Disulfide bond formation in prokaryotes and eukaryotes * Quality control in the export pathway * Import of proteins into organelles * The secretory pathway * Vesicular transport * Spectacular color throughout.
Carrier Form: 1 online resource (xiv, 424 pages) : illustrations (some color)
Bibliography: Includes bibliographical references and index.
ISBN: 9780122007316
012200731X
9780080480503
0080480500
Index Number: QP551
CLC: Q51
Contents: Introduction -- Overview -- Methods in Protein Targeting, Translocation and Transport -- Targeting Sequences -- Protein Export in Bacteria -- Protein Sorting at the Membrane of the Endoplasmic Reticulum -- Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum -- Disulfide Bond Formation in Prokaryotes and Eukaryotes -- The Unfolded Protein Response -- Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection -- Translocation of Proteins into Mitochondria -- The Import and Sorting of Protein into Chloroplasts -- Import of Proteins into Peroxisomes -- Nucleocytoplasmic Transport -- Protein Transport to the Yeast Vacuole -- The Secretory Pathway -- Vesicular Transport -- Conclusion/Perspective.
Introduction/overview -- Ross E. Dalbey, Gunnar von Heijne -- Methods in protein targeting, translocation and transport / Ross E. Dalbey, Minyong Chen, Martin Wiedmann -- Targeting sequences / Gunnar von Heijne -- Protein export in bacteria / Arnold J.M. Driessen, Chris van der Does -- Protein sorting at the membrane of the endoplasmic reticulum / Nora G. Haigh, Arthur E. Johnson -- Membrane protein insertion into bacterial membranes and the endoplasmic reticulum / Andreas Kuhn, Martin Spiess -- Disulfide bond formation in prokaryotes and eukaryotes / James Regeimbal, James C.A. Bardwell -- The unfolded protein response / Carmela Sidrauski, Jason H. Brickner, Peter Walter -- Protein quality control in the export pathway: the endoplasmic reticulum and its cytoplasmic proteasome connection / Zlatka Kostova, Dieter H. Wolf -- Translocation of proteins into mitochondria / Thorsten Prinz, Nikolaus Pfanner, Kaye N. Truscott -- The import and sorting of protein in chloroplasts / Ju rgen Soll, Colin Robinson, Lisa Heins -- Import of proteins into peroxisomes / Suresh Subramani [and others] -- Nucleocytoplasmic transport / Dirk Go rlich, Stefan Ja kel -- Protein transport to the yeast vacuole / Todd R. Graham, Steven F. Nothwehr -- The secretory pathway / Benjamin S. Glick -- Vesicular transport / Joachim Ostermann, Tobias Stauber, Tommy Nilsson -- Conclusion/perspective / Ross E. Dalbey, Gunnar von Heijne.

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