Cross-over trials in clinical research
Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over...
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Main Authors: | |
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Published: |
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Literature type: | Electronic eBook |
Language: | English |
Edition: | 2nd ed. |
Series: |
Statistics in practice
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Subjects: | |
Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/0470854596 |
Summary: |
Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. |
Carrier Form: | 1 online resource (xv, 345 pages) : illustrations. |
Bibliography: | Includes bibliographical references (pages 323-334) and indexes. |
ISBN: |
0470854588 9780470854587 0470854596 9780470854594 |
Index Number: | R853 |
CLC: | R311 |
Contents: | Some basic considerations concerning estimation in clinical trials -- The AB/BA design with normal data -- Other outcomes and the AB/BA design -- Normal data from designs with three or more treatments -- Other outcomes from designs with three or more treatments -- Some special designs -- Graphical and tabular presentation of cross-over trials -- Various design issues -- Mathematical approaches to carry-over. |