Cross-over trials in clinical research

Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over...

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Bibliographic Details
Main Authors: Senn, Stephen
Published:
Literature type: Electronic eBook
Language: English
Edition: 2nd ed.
Series: Statistics in practice
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/0470854596
Summary: Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages.
Carrier Form: 1 online resource (xv, 345 pages) : illustrations.
Bibliography: Includes bibliographical references (pages 323-334) and indexes.
ISBN: 0470854588
9780470854587
0470854596
9780470854594
Index Number: R853
CLC: R311
Contents: Some basic considerations concerning estimation in clinical trials -- The AB/BA design with normal data -- Other outcomes and the AB/BA design -- Normal data from designs with three or more treatments -- Other outcomes from designs with three or more treatments -- Some special designs -- Graphical and tabular presentation of cross-over trials -- Various design issues -- Mathematical approaches to carry-over.