Screen LibraryTranslating Molecules into Medicines : Cross-Functional Integration at the Drug Discovery-Development Interface /
Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understandin...
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| Corporate Authors: | |
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| Group Author: | ; ; ; |
| Published: |
Springer International Publishing : Imprint: Springer,
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| Publisher Address: | Cham : |
| Publication Dates: | 2017. |
| Literature type: | eBook |
| Language: | English |
| Series: |
AAPS Advances in the Pharmaceutical Sciences Series,
25 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-3-319-50042-3 |
| Summary: |
Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book al |
| Carrier Form: | 1 online resource (XXIV, 461 pages) : illustrations. |
| ISBN: | 9783319500423 |
| Index Number: | RS380 |
| CLC: | R914 |
| Contents: | Pharmaceutical Industry Performance -- Scope: productivity, success rates and costs -- Competitive landscape and regulatory requirements across different geographies. Drivers for increased efficiency, innovative approaches, and outlook for the next decade -- Unmet needs, major therapeutic areas of R&D focus and investment -- New Product Planning: Scope: General overview of patient profiles from different therapeutic areas, competitive intelligence, standard of care considerations, and impact of this information on the definition of NCE and product attributes and timelines -- Discovery Chemis |