RNA therapeutics /

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence...

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Bibliographic Details
Group Author: Garner, Amanda L
Published: Springer,
Publisher Address: Cham, Switzerland :
Publication Dates: [2018]
Literature type: Book
Language: English
Series: Topics in medicinal chemistry, 27
Subjects:
Summary: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant as
Carrier Form: vii, 259 pages : illustrations (some color) ; 25 cm.
Bibliography: Includes bibliographical references and index.
ISBN: 9783319680903
3319680900
Index Number: RM301
CLC: Q522
Call Number: Q522/R486-21
Contents: Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching -- A Modular Approach to the Discovery and Affinity Maturation of Sequence-Selective RNA-Binding Compounds -- Structure-Based Discovery of Small Molecules Binding to RNA -- Approaches for the Discovery of Small Molecule Ligands Targeting microRNAs -- Viral RNA Targets and Their Small Molecule Ligands -- Drugging Pre-mRNA Splicing -- Targeting RNA G-Quadruplexes for Potential Therapeutic Applications -- The Therapeutic Targeting of Long Noncoding RNA -- M