Medical biochemistry /
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Main Authors: | |
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Corporate Authors: | |
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Published: |
Academic Press,
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Publisher Address: | London, United Kingdom : |
Publication Dates: | 2017. |
Literature type: | eBook |
Language: | English |
Subjects: | |
Online Access: |
http://www.sciencedirect.com/science/book/9780128035504 https://www.sciencedirect.com/science/book/9780128035504 |
Item Description: | 1. Chemical composition of living beings 2. Water 3. Proteins 4. Carbohydrates 5. Lipids 6. Nucleic Acids 7. Elements of Thermodynamics and Chemical Kinetics 8. Enzymes 9. Biological Oxidations: Bioenergetics 10. Antioxidants 11. Membranes 12. Digestion: Absorption 13. Metabolism 14. Metabolism of carbohydrates 15. Metabolism of lipids 16. Metabolism of amino acids 17. Metabolism of heme 18. Metabolism of purines and pirimidines 19. Integration and regulation of metabolism 20. Metabolism in some tissues 21. Genetic Information I: Replication and transcription 22. Genetic Information II: Biosynthesis 23. Regulation of Genetic Expression 24. Post-translational modifications of proteins 25. Biochemical bases of endocrinology (I) 26. Biochemical bases of endocrinology (II) 27. Vitamins 28. Water balance and acid-base equilibrium 29. Essential minerals 30. Molecular bases of immunity 31. Hemostasia 32. Apoptosis. |
Carrier Form: | 1 online resource (826 pages) |
ISBN: |
9780128035870 0128035870 |
Index Number: | RB112 |
CLC: | R362 |
Contents: | Machine generated contents note: 1.Chemical Composition of Living Beings -- Biogenic Elements -- Biological Compounds -- Summary -- Bibliography -- 2.Water -- The Water Molecule is Polar -- Hydrogen Bond -- Water as Solvent -- Water as an Electrolyte -- Equilibrium Constant -- Equilibrium of Water Ionization -- Acids and Bases -- Acids and Bases Strength -- pH -- Buffers -- Titration Curve of Acids and Bases -- Appendix -- Summary -- Bibliography -- 3.Proteins -- Proteins are Macromolecules Formed by Amino Acids -- Amino Acids -- Peptides -- Proteins -- Collagen -- Keratins -- Hemoglobin -- Heme -- Globin -- Hemoglobin Derivatives -- Abnormal Hemoglobins -- Blood Plasma Proteins -- Main Proteins in Blood Plasma -- Muscle Proteins -- Muscle Contraction -- Summary -- Bibliography -- 4.Carbohydrates -- Monosaccharides -- Disaccharides -- Polysaccharides -- Summary -- Bibliography -- 5.Lipids -- Classification -- Fatty Acids -- Essential Fatty Acids -- Simple Lipids -- Complex Lipids -- Substances Associated with Lipids -- Summary -- Bibliography -- 6.Nucleic Acids -- Nucleotides -- Nucleic Acids -- Virus -- Free Nucleotides -- Summary -- Bibliography -- 7.Elements of Thermodynamics and Biochemical Kinetics -- Thermodynamics -- Chemical Kinetics -- Summary -- Bibliography -- 8.Enzymes -- Enzymes are Biological Catalysts -- Nomenclature and Classification of Enzymes -- Chemical Nature of Enzymes -- Metalloenzymes -- Enzymatic Catalysis -- Active Site -- Zymogens -- Genetic Alterations that Affect Enzyme Function -- Enzyme Distribution Within the Cell -- Multienzyme Systems -- Determination of Enzyme Activity -- Factors that Modify Enzyme Activity -- Enzyme Inhibitors -- Regulation of Enzyme Activity -- Constitutive and Inducible Enzymes -- Enzymatic Processes in Cascade -- Isozymes -- Determination of Enzymes in the Clinical Laboratory -- Summary -- Bibliography -- 9.Biological Oxidations: Bioenergetics -- The Energy-Rich Intermediate ATP -- Oxidation-Reduction -- Biological Oxidations -- Respiratory Chain -- Oxidative Phosphorylation -- Phosphorylation at Substrate Level -- Other Electron Transport Systems -- Summary -- Bibliography -- 10.Antioxidants -- Reactive Species -- Summary -- Bibliography -- 11.Membranes -- Structure -- Transport Across Membranes -- Passive Transport or Facilitated Diffusion -- Active Transport -- Summary -- Bibliography -- 12.Digestion -- Absorption -- Saliva -- Gastric Juice -- Pancreatic Juice -- Intestinal Mucosa -- Bile -- Summary of the Digestive Process -- Absorption -- Summary -- Bibliography -- 13.Metabolism -- Metabolic Pathways -- Metabolic Studies -- Regulation of Metabolism -- Summary -- Bibliography -- 14.Carbohydrate Metabolism -- Glucose Uptake Into Cells -- Glucose Phosphorylation -- Metabolic Pathways for Glucose -- Metabolism of Other Hexoses -- Biosynthesis of the Oligosaccharides of Glycoproteins -- Summary -- Bibliography -- 15.Lipid Metabolism -- Blood Lipids -- Plasma Lipoproteins -- Tissue Lipids -- Fat Metabolism -- Fatty Acid Catabolism -- Fatty Acid Biosynthesis -- Eicosanoid Biosynthesis -- Triacylglycerol Biosynthesis -- Biosynthesis of Phospholipids -- Congenital Disorders of Complex Lipid Catabolism -- Cholesterol Metabolism -- Cholesterol Biosynthesis -- Summary -- Bibliography -- 16.Amino Acid Metabolism -- Essential Amino Acids -- Amino Acid Catabolism -- Metabolic Pathways of Ammonia -- Other General Mechanisms of Amino Acid Metabolism -- Metabolic Pathways of Amino Acids -- Summary -- Bibliography -- 17.Heme Metabolism -- Heme Biosynthesis -- Catabolism of Heme -- Summary -- Bibliography -- 18.Purine and Pyrimidine Metabolism -- Purine Biosynthesis -- Purine Salvage Pathway -- Purine Catabolism -- Uric Acid -- Gout -- Pyrimidine Biosynthesis -- Pyrimidine Catabolism -- Di- and Triphosphate Nucleoside Biosynthesis -- Deoxyribonucleotide Biosynthesis -- Pharmacological Applications -- Summary -- Bibliography -- 19.Integration and Regulation of Metabolism -- Metabolic Integration -- Metabolic Regulation -- Summary -- Bibliography -- 20.Metabolism in Some Tissues -- Liver Metabolism -- Skeletal Muscle Metabolism -- Heart Metabolism -- Adipose Tissue Metabolism -- Nervous Tissue Metabolism -- Summary -- Bibliography -- 21.The Genetic Information (I) -- DNA Replication -- Transcription -- Methods Used in Molecular Biology -- Summary -- Bibliography -- 22.The Genetic Information (II) -- Protein Biosynthesis -- Mechanism of Protein Biosynthesis -- Genetic Mutations -- Oncogenes -- Epigenetics -- Summary -- Bibliography -- 23.Regulation of Gene Expression -- Gene Regulation in Eukaryotes -- Structure of Gene Regulatory Proteins -- Role of Noncoding RNAs -- Small RNAs -- RNA Interference -- Long Noncoding RNA -- Riboswitches -- CRISPR -- Summary -- Bibliography -- 24.Posttranslational Protein Modifications Protein Folding -- Pathologies Caused by Misfolded Proteins -- Posttranslational Protein Modifications -- ADP-Ribosylation -- Ubiquitination -- Sumoylati |