Screen LibraryHandbook of neuroemergency clinical trials /
During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell b...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Elsevier Academic Press,
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| Publisher Address: | Amsterdam ; Boston : |
| Publication Dates: | 2006. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780126480825 |
| Summary: |
During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical a |
| Carrier Form: | 1 online resource (xviii, 336 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780126480825 0126480826 0080454356 9780080454351 1280630787 9781280630781 |
| Index Number: | RC346 |
| CLC: | R741 |
| Contents: |
Acute ischemic stroke / Subarachnoid hemorrhage / Spontaneous intracerebral hemorrhage / Traumatic brain injury / Acute seizures and status epilepticus / Clinical trials in neuro-ophthalmology / Brain resuscitation / Clinical trials in brain injury after cardiac arrest / Efficient dose |