Screen LibraryStructure and physics of viruses an integrated textbook /
This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losin...
Saved in:
| Corporate Authors: | |
|---|---|
| Group Author: | |
| Published: |
|
| Literature type: | Electronic eBook |
| Language: | English |
| Series: |
Subcellular biochemistry,
68 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-94-007-6552-8 |
| Summary: |
This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdo |
| Item Description: | Includes indexes. |
| Carrier Form: | 1 online resource (xix, 728 p.) : ill. |
| ISBN: |
9789400765528 (electronic bk.) 9400765525 (electronic bk.) |
| Index Number: | QR360 |
| CLC: | Q939.4 |
| Contents: |
The Viral Machine. Introduction: The Structural Basis of Virus Function / The Basic Architecture of Viruses / Determination of the Structure and Physical Properties of Viruses. Conventional Electron Microscopy, Cryo-Electron Microscopy and Cryo-Electron Tomography of Viruses / X-Ray Crystallography of Viruses / Nuclear Magnetic Resonance Spectroscopy to Study Virus Structure / Fluorescence, Circular Dichroism and Mass Spectrometry as Tools to Study Virus Structure / Combined Approaches to Study Virus Structures / Atomic Force Microscopy of Viruses / Optical Tweezers to Study Viruses / Structural Foundations of Virus Properties and Functions. Assembly of Simple Icosahedral Viruses / Structure and Assembly of Complex Viruses / Nucleic Acid Packaging in Viruses / Virus Maturation / Virus Morphogenesis in the Cell: Methods and Observations / Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells / Entry of Enveloped Viruses into Host Cells: Membrane Fusion / Bacteriophage Receptor Recognition and Nucleic Acid Transfer / Mechanical Properties of Viruses / Theoretical Studies on Assembly, Physical Stability and Dynamics of Viruses / Applied Structural and Physical Virology. Antiviral Agents: Structural Basis of Action and Rational Design / Design of Novel Vaccines Based on Virus-Like Particles or Chimeric Virions / Nanoscale Science and Technology with Plant Viruses and Bacteriophages / |