Mechanisms and emerging therapies in tremor disorders /

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influen...

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Bibliographic Details
Corporate Authors: SpringerLink (Online service)
Group Author: Grimaldi, Giuliana; Manto, Mario
Published: Springer,
Publisher Address: New York, NY :
Publication Dates: 2013.
Literature type: eBook
Language: English
Series: Contemporary clinical neuroscience
Subjects:
Online Access: http://dx.doi.org/10.1007/978-1-4614-4027-7
Summary: Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented.
Carrier Form: 1 online resource.
Bibliography: Includes bibliographical references and index.
ISBN: 9781461440277 (electronic bk.)
1461440270 (electronic bk.)
Index Number: RC376
CLC: R742.5
R874
Contents: Fundamental aspects --
Definition of Tremor /
Membrane Mechanisms of Tremor /
Rodent Models of Tremor /
Advances in the Genetics of Human Tremor /
Musculoskeletal Models of Tremor /
The various forms of tremor in clinical practice: presentation and mechanisms --
Physiologic Tremor /
Rest Tremor /
Postural Tremors /
Isometric Tremor /
Essential Tremor and Other Forms of Kinetic Tremor /
Dystonic Tremor /
Orthostatic Tremor /
Vocal Tremor /
Update in Familial Cortical Myoclonic Tremor with Epilepsy /
Posttraumatic Tremor and Other Posttraumatic Movement Disorders /
Psychogenic Tremor /
Tremor in Childhood /
Assessment of tremor: clinical, neurophysiological and neuroimaging aspects --
Assessment of Tremor: Clinical and Functional Scales /
Instrumentation: Classical and Emerging Techniques /
Signal Processing /
Diffusion Imaging in Tremor /
Metabolic Networks in Parkinson's Disease /
Therapies of tremor --
Pharmacological Treatments of Tremor /
Thalamotomy /
Deep Brain Stimulation /
Dopaminergic Influences on Rest and Action Parkinsonian Tremors and Emerging Therapies for Tremor /