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Integrins : molecular and biological responses to the extracellular matrix /

Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered in Receptors for Extracellular Matrix. It addresse...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Cheresh, David A.; Mecham, Robert P.
Published: Academic Press,
Publisher Address: San Diego :
Publication Dates: 1994.
Literature type: eBook
Language: English
Series: Biology of extracellular matrix series
Subjects:
Integrins.
MEDICAL > Biochemistry.
Inte grine.
Matrice extracellulaire.
Biologia molecular e macromolecular.
Inte grines.
Integrine.
Humans > Proteins
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780080917290
Summary: Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered in Receptors for Extracellular Matrix. It addresses some of the most exciting areas of integrin biology, including the varied roles of integrins in cell division, differentiation, movement, wound healing, inflammation, thrombosis, osteoporosis, and cancer. Key Features * Describes key aspects of integrin structure, function, and biology * Covers collagen receptors, epithelial cell integrins, leukocyte integrins, platelet integrins, integrin signaling, and integrin antagonists * Investigates the expression and role of integrins during development and in the cytoskeleton * Includes the actions and influences of integrins in inflammation, thrombosis, and osteoporosis.
Carrier Form: 1 online resource (xiv, 278 pages) : illustrations.
Bibliography: Includes bibliographical references and index.
Index Number: QP552
CLC: Q51
Contents: Structural basis of integrin-ligand (RGD) interaction / Jeffrey W. Smith -- Integrins as signal transducing receptors / Martin A. Schwartz -- Interactions between integrins and the cytoskeleton: structure and regulation / Keiko O. Simon, Keith Burridge -- Integrins, signaling and the remodeling of the extracellular matrix / John Ashkenas [and others] -- Integrins in the development / Thomas Lallier, Mark D. Hens, Douglas W. Desimone -- Distinctive functions of [alpha]6[beta]4 and other integrins in epithelial cells / Vito Quaranta [and others].
Leukocyte integrins / Mariano J. Elices -- Molecular properties of human platelet integrin [alpha]IIb[beta] / Thomas J. Kunicki, Zaverio M. Ruggeri -- Therapeutic potential of integrin antagonists / Jeffrey M. Stadel [and others].

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