Advances in cancer research. Volume 141, Cancer stem cells /
Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network co...
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Group Author: | ; ; ; |
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Published: |
Academic Press,
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Publisher Address: | Cambridge, MA : |
Publication Dates: | 2019. |
Literature type: | Book |
Language: | English |
Edition: | First edition. |
Series: |
Advances in cancer research,
volume 141 |
Subjects: | |
Summary: |
Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network control of cancer stem cell properties, Dormancy and the cancer cell niche, Clonal hematopoiesis: A hematopoietic stem cell disorder of aging, Stringent assays to study human breast cancer stem cells, Regulation of breast cancer stem cell specification and maintenance by hypoxia-inducible factors, Cancer stem cells in breast and prostate: fact or fiction, and much more. |
Carrier Form: | xiii, 253 pages : illustrations (some color) ; 24 cm. |
Bibliography: | Includes bibliographical references. |
ISBN: |
9780128149942 0128149949 |
Index Number: | RC268 |
CLC: | R73-1 |
Call Number: | R73-1/A244/v.141 |
Contents: | Front Cover; Cancer Stem Cells; Copyright; Contents; Contributors; Preface; References; Chapter One: Regulation of cancer stem cell properties by SIX1, a member of the PAX-SIX-EYA-DACH network; 1. Introduction; 2. Cancer stem cells (CSCs); 3. SIX1 and CSCs; 4. Sustained proliferative signaling; 5. Evading growth suppressors; 6. Enabling replicative immortality; 7. Resisting cell death; 8. Genome instability and mutation; 9. Deregulating cellular energetics; 10. Inducing angiogenesis; 11. Regulation of SIX1 expression; 12. SIX1 clinical significance; 13. EYA; 14. DACH; 15. Concluding remarks. |