Screen LibraryThe mRNA metabolism in human disease /
The eukaryotic gene expression pathway involves a number of interlinked steps, with messenger RNA (mRNA) being the key intermediate. The precursor mRNA is transcribed from DNA, processed by removal of introns and addition of the cap structure and the poly(A) tail. The mature mRNA is then exported to...
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| Group Author: | |
|---|---|
| Published: |
Springer,
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| Publisher Address: | Cham, Switzerland : |
| Publication Dates: | [2019] |
| Literature type: | Book |
| Language: | English |
| Series: |
Advances in experimental medicine and biology,
volume 1157 |
| Subjects: | |
| Summary: |
The eukaryotic gene expression pathway involves a number of interlinked steps, with messenger RNA (mRNA) being the key intermediate. The precursor mRNA is transcribed from DNA, processed by removal of introns and addition of the cap structure and the poly(A) tail. The mature mRNA is then exported to the cytoplasm where it is translated into protein and finally degraded. In this process, mRNA is associated with RNA-binding proteins forming ribonucleoprotein complexes, whose protein content evolves throughout the lifetime of the mRNA. While the complexity of eukaryotic gene expression allows t |
| Carrier Form: | ix, 180 pages : illustrations (chiefly color) ; 26 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9783030199654 3030199657 |
| Index Number: | RB155 |
| CLC: |
Q522 R394 |
| Call Number: | R394/M584 |