Optimization in HPLC: concepts and strategies /
Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules,...
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Corporate Authors: | ; |
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Group Author: | |
Published: |
Wiley-VCH,
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Publisher Address: | Weinheim, Germany : |
Publication Dates: | 2021 |
Literature type: | eBook |
Language: | English |
Subjects: | |
Online Access: |
https://onlinelibrary.wiley.com/doi/book/10.1002/9783527837489 |
Summary: |
Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes |
Item Description: | Description based on print version record. |
Carrier Form: |
1 online resource (416 pages) Also available in print. |
Bibliography: | Includes bibliographical references and index |
ISBN: |
9783527837489 (electronic book) 9783527828500 9783527347896 |
Index Number: | QP519 |
CLC: | O658.1 |
Contents: | Optimization Strategies for Different Modes and Uses of HPLC. 2D-HPLC- Method Development for Successful Separations / Dwight R Stoll, PhD -- Do you HILIC? With Mass Spectrometry? Then do it Systematically / Thomas Letzel -- Optimization Strategies in LC-MS Method Development / Markus M Martin -- Chromatographic Strategies for the Successful Characterization of Protein Biopharmaceuticals / Szabolcs Fekete, Valentina D'Atri, Davy Guillarme -- Optimization Strategies in HPLC for the Separation of Biomolecules / Lisa Strasser, Florian Fossl, Jonathan Bones -- Optimization Strategies in Packed-Column Supercritical Fluid Chromatography (SFC) / Caroline West -- Strategies for Enantioselective (Chiral) Separations / Markus Juza -- Optimization Strategies Based on the Structure of the Analytes / Christoph A Fleckenstein -- Optimization Opportunities in a Regulated Environment / Stavros Kromidas -- Computer-aided Optimization. Strategy for Automated Development of Reversed-Phase HPLC Methods for Domain-Specific Characterization of Monoclonal Antibodies / Jennifer La, Mark Condina, Leexin Chong, Craig Kyngdon, Matthias Zimmermann, Sergey Galushko -- Fusion QbD Software Implementation of APLM Best Practices for Analytical Method Development, Validation, and Transfer / Richard Verseput -- Current Challenges for HPLC Users in Industry. Modern HPLC Method Development / Stefan Lamotte -- Optimization Strategies in HPLC from the Perspective of an Industrial Service Provider / Juri Leonhardt, Michael Haustein -- Optimization Strategies in HPLC from the Perspective of a Service Provider - The UNTIE Process of the CUP Laboratories / Dirk Freitag-Stechl, Melanie Janich -- Optimization Strategies in HPLC / Bernard Burn -- Current Challenges for HPLC Equipment Suppliers. Optimization Strategies with your HPLC- Agilent Technologies / Jens Trafkowski -- To Empower the Customer - Optimization Through Individualization / Kristin Folmert, Kathryn Monks -- (U)HPLC Basics and Beyond / Gesa Schad, Brigitte Bollig, Kyoko Watanabe -- Addressing Analytical Challenges in a Modern HPLC Laboratory / Frank Steiner, Soo Hyun Park -- Systematic Method Development with an Analytical quality-by-Design Approach Supported by Fusion QbD and UPLC-MS / Falk-Thilo Ferse, Detlev Kurth, Tran N Pham, Fadi L Alkhateeb, Paul Rainville |