Neurodegeneration and neuroprotection in Parkinson's disease /

Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiol...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Olanow, C. W. (Charles Warren), 1941- (Editor); Jenner, Peter, 1946- (Editor); Youdim, Moussa B. H. (Editor)
Published: Academic Press,
Publisher Address: London ; San Diego :
Publication Dates: 1996.
Literature type: eBook
Language: English
Series: Neuroscience perspectives
Subjects:
Online Access: http://www.sciencedirect.com/science/book/9780125254458
Summary: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.
Carrier Form: 1 online resource (xii, 224 pages) : illustrations.
Bibliography: Includes bibliographical references and index.
ISBN: 9780125254458
0125254458
9780080537412
0080537413
1281033421
9781281033420
Index Number: RC382
CLC: R742.5
Contents: Oxidative stress, brain iron and neurodegeneration : basic principles / John M.C. Gutteridge and Barry Halliwell -- Pathological evidence for oxidative stress in Parkinson's disease and related degenerative disorders / P. Jenner and C.W. Olanow -- Treatment of Parkinson's disease with deprenyl (selegiline) and other monoamine oxidase inhibitors / Karl Kieburtz and Ira Shoulson -- Iron and neurodegeneration : prospects for neuroprotection / C.W. Olanow and M.B.H. Youdim -- Nitrone radical traps protect in experimental neurodegenerative diseases / Robert A. Floyd and John M. Carney -- Therapeutic effects of nitric oxide synthase inhibition in neuronal injury / M. Flint Beal -- Mitochondrial dysfunction in neurodegeneration : prospects for neuroprotection / A.H.V. Schapira -- Bioenergetics and excitotoxicity : the weak excitotoxic hypothesis / James G. Greene and J. Timothy Greenamyre -- Calcium ions in necrotic and apoptotic cell death / Pierluigi Nicotera and Sten Orrenius -- Neurotrophic factors : towards a restorative therapy of Parkinson's disease / C. Anthony Altar, Stanley J. Wiegand, Ronald M. Lindsay and Jesse M. Cedarbaum -- Immune-mediated cell death and neuroprotection in neurodegenerative diseases / Stanley H. Appel, R. Glenn Smith and Wei Dong Le -- Reduction of neuronal apoptosis by small molecules : promise for new approaches to neurological therapy / William G. Tatton, William Y.H. Ju, J. Wadia and Nadine A. Tatton.
Oxidant Stress: -- J.M.C. Gutteridge and B. Halliwell, Oxidative Stress, Brain Iron, and Neurodegeneration: Basic Principles. -- P. Jenner and C.W. Olanow, Pathological Evidence for Oxidative Stress in Parkinson's Disease and Related Degenerative Disorders. -- K. Kieburtz and I. Shoulson, Treatment of Parkinson's Disease with Deprenyl (Selegiline) and Other Mondamine Oxidase Inhibitors. -- C.W. Olanow and M.B.H. Youdim, Iron and Nuerodegeneration: Prospects for Neuroprotection. -- R.A. Floyd and J.M. Carney, Nitrone Radical traps (NRTs) Protect in Experimental Neurodegenerative Diseases. -- M. Flint Beal, Therapeutic Effects of NOS Inhibition in Neuronal Injury. Mitochodrial Toxicity: -- A.H.V Schapira, Mitochondrial Dysfunction in Neurodegeneration: Prospects for Neuroprotection. -- Excitatory Neurotoxicity: -- J.G. Greene and J.T. Greenamyre, Bioenergetics and Exitotoxicity: The Weak Excitotoxic Hypothesis. -- Calcium Exitatory Toxicity: -- P. Nicotera and S. Orrenius, Calcium Ions in Necrotic and Apoptotic Cell Death. Trophic Factors: -- C.A. Altar, S.J. Wiegand, R.M. Lindsay, and J.M. Cedarbaum, Neurotrophic Factors: Towards a Restorative Therapy of Parkinson's Disease. -- Immune Mechanisms: -- S.H. Appel, R.G. Smith, and W.D. Le, Immuno-Mediated Cell Death and Neuroprotection in Neurodegenerative Diseases. -- Apoptosis: -- W.G. Tatton, M.Y.H. Ju, J. Wadia, and N.A. Tatton, Reduction of Neuronal Apoptosis by Small Molecules: Promise for New Approaches to Neurological Therapy. Subject Index.