Screen LibraryEssential concepts in toxicogenomics
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| Corporate Authors: | |
|---|---|
| Group Author: | ; |
| Published: |
Humana Press,
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| Publisher Address: | Totowa, N.J. |
| Publication Dates: | c2008. |
| Literature type: | Book |
| Language: | English |
| Series: |
Methods in molecular biology ; v. 460 |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-1-60327-048-9 |
| Carrier Form: | 1 online resource (xi, 277 p., 8 p. of plates): ill. (some col.) |
| ISBN: |
9781603270489 (electronic bk.) 1603270485 (electronic bk.) |
| Index Number: | R394 |
| CLC: | R394.6 |
| Contents: |
Description based on print version record. Includes bibliographical references and index. Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge. |