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Hepatic plasma proteins : mechanisms of function and regulation /

Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities;...

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Bibliographic Details
Main Authors: Bowman, Barbara H.
Corporate Authors: Elsevier Science & Technology.
Published: Academic Press,
Publisher Address: San Diego :
Publication Dates: 1993.
Literature type: eBook
Language: English
Subjects:
Blood proteins.
Liver > metabolism.
Blood Proteins > biosynthesis.
Blood Proteins > genetics.
Blood Proteins > physiology.
Liver > Physiology.
Prote ines plasmatiques.
Foie > Me tabolisme.
MEDICAL > Physiology.
SCIENCE > Human Anatomy & Physiology. > Human Anatomy & Physiology.
Prote ines sang.
Foie > Physiologie.
Humans > Blood
Electronic books.
Online Access: http://www.sciencedirect.com/science/book/9780121210700
Summary: Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.
Carrier Form: 1 online resource (xii, 285 pages) : illustrations
Bibliography: Includes bibliographical references (pages 207-276) and index.
ISBN: 9781483216508
1483216500
Index Number: QP99
CLC: R331.1
Contents: Physiological and clinical implications of human plasma protein abnormalities -- Coagulation factors -- Plasma protease inhibitors -- Complement factors -- Apolipoproteins -- Acute-phase reactants -- [alpha]1-acid glycoprotein -- C-reactive protein -- Serum amyloid protein -- Serum amyloid A -- Complement 3 -- [alpha]2-HS-glycoprotein -- Albumin -- Plasma proteinase inhibitors -- Variety of human plasma proteinase inhibitors -- [alpha]1-antitrypsin -- Plasma protein vehicles -- Transferrin -- Ceruloplasmin -- Transthyretin and the retinol binding protein -- Haptoglobin -- Hemopexin -- Vitamin D binding protein -- Biochemical regulators: cytokines and transcription factors -- Cytokines regulate changes in plasma protein synthesis -- Transcription factors in the nucleus regulate plasma protein gene expression by binding to specific DNA sequences -- Transcription factors interact with DNA sequences of plasma protein genes.

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