NMR in pharmaceutical sciences /

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Bibliographic Details
Group Author: Everett, Jeremy R. (Editor); Harris, Robin K. (Robin Kingsley) (Editor); Lindon, John C. (Editor); Wilson, Ian D. (Editor)
Published: John Wiley & Sons,
Publisher Address: Chichester, UK :
Publication Dates: 2015.
Literature type: Book
Language: English
Series: eMagRes books
Subjects:
Carrier Form: xv, 479 pages : illustrations (some color) ; 26 cm.
Bibliography: Includes bibliographical references and index.
ISBN: 9781118660256
1118660250
Index Number: RM301
CLC: R914
R917
Call Number: R917/N964-3
Contents: Drug discovery and development : the role of NMR -- Modern NMR pulse sequences in pharmaceutical R & D -- Experimental NMR methods for pharmaceutical research and development -- 19f NMR spectroscopy : applications in pharmaceutical studies -- Quantitative NMR spectroscopy in pharmaceutical R & D -- High-throughput NMR in pharmaceutical R & D -- Multivariate data analysis methods for pharmaceutical NMR -- The role of NMR in target identification & validation for pharmaceutical R & D -- High resolution MAS NMR of tissues and cells -- NMR studies of inborn errors of metabolism -- NMR-based structure confirmation of hits & leads in pharmaceutical R & D -- Fragment-based drug design using NMR methods -- Hit discovery from natural products in pharmaceutical R & D -- NMR-based structure determination of drug leads and candidates -- Mixture analysis in pharmaceutical r & d using hyphenated NMR techniques -- Conformation and stereochemical analysis of drug molecules -- NMR methods for the assignment of absolute stereochemistry of bioactive compounds -- Applications of preclinical MRI/MRS in the evaluation of drug efficacy and safety -- Pre-clinical drug metabolism using NMR -- Pre-clinical drug efficacy and safety using NMR spectroscopy -- Characterization of pharmaceutical compounds by solid-state NMR -- Structure-based drug design using NMR -- Pharmaceutical technology studied by MRI -- NMR-based metabolic phenotyping for disease diagnosis & stratification -- NMR-based pharmacometabonomics : a new approach to personalised medicine -- Clinical MRI studies of drug efficacy & safety -- The role of NMR in the protection of intellectual property in pharmaceutical R & D -- Analysis of counterfeit medicines and adulterated dietary supplements by NMR -- Pharmaceutical industry : regulatory control and impact on NMR spectroscopy -- NMR spectroscopy in the European & US pharmacopoeias -- NMR in pharmaceutical manufacturing.