Transcriptomics and gene regulation /

This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and st...

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Bibliographic Details
Group Author: Kim, Dong; Wu, Jiaqian
Published: Springer,
Publisher Address: Dordrecht :
Publication Dates: [2016]
Literature type: Book
Language: English
Series: Translational Bioinformatics, 9
Subjects:
Summary: This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expres
Carrier Form: x, 185 pages : color illustrations, color portraits ; 25 cm.
Bibliography: Includes bibliographical references.
ISBN: 9789401774482
940177448X
Index Number: QH450
CLC: Q756
Call Number: Q756/T772
Contents: The Analyses of Global Gene Expression and Transcription Factor Regulation -- Global Approaches to Alternative Splicing and its Regulation -- Recent Advances and Open Questions -- Long Non-coding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System -- Gene expression models of signaling pathways -- From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases -- Introduction to Isoform Sequencing using Pacific Biosciences Technology (Iso-Seq) -- Systematic and Integrative Analysis of Gene Expression to Identify Feature Gen