Screen LibraryRecombinant antibodies for immunotherapy
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| Group Author: | |
|---|---|
| Published: |
Cambridge University Press,
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| Publisher Address: | New York |
| Publication Dates: | 2009. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xiv, 419 p.: ill. (some col.) ; 27 cm. |
| ISBN: |
9780521887328 (hardback) 0521887321 (hardback) |
| Index Number: | R392 |
| CLC: | R392.11 |
| Call Number: | R392.11/R311 |
| Contents: |
Includes bibliographical references and index. Humanization of recombinant antibodies / José W. Saldanha -- Immunogenicity assessment of antibody therapeutics / Philippe Stas ... [et al.] -- In vitro screening for antibody immunogenicity / Frank J. Carr and Matthew B. Baker -- Antibody libraries from naïve V gene sources / Gerald Beste and David Lowe -- Antibodies from IgM libraries / Stefan Knackmuss and Vera Molkenthin -- Generation and screening of synthetic human combinatorial antibody library HuCAL GOLD / Ingo M. Klagge -- Therapeutic antibodies from XenoMouse transgenic mice / Aya Jakobovits -- VelocImmune : immunoglobulin variable region humanized mice / Andrew Murphy -- Mechanisms of tumour cell killing by therapeutic antibodies / Ross Stewart and Carl Webster -- Optimization of Fc domains to enhance antibody therapeutics / Greg A. Lazar and Aaron K. Chamberlain -- Glycoengineered therapeutic antibodies / Peter Brünker, Peter Sondermann, and Pablo Umaña -- Monoclonal antibodies for the delivery of cytotoxic drugs / David J. King -- Immunotherapy with radio-immune conjugates / Christina A. Kousparou and Agamemnon A. Epenetos -- Immunotherapeutic antibody fusion proteins / Nigel S. Courtenay-Luck and David Jones -- Alternative antibody formats / Fabrice Le Gall and Melvyn Little -- Single-domain antibodies / Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, and Dirk Saerens -- Engineering of non-CDR loops in immunoglobulin domains / Florian Rüker and Gordana Wozniak-Knopp -- Alternative scaffolds : expanding the options of antibodies / Andreas Plückthun -- Polymer fusions to increase antibody half-lives : PEGylation and other modifications / Sam P. Heywood and David P. Humphreys -- Extending antibody half-lives with albumin / Jan Terje Andersen and Inger Sandlie -- A stem cell-based platform for the discovery and development of antitumor therapeutic antibodies to novel targets / Jennie P. Mather ... [et al.] -- Antibody directed enzyme prodrug therapy (ADEPT) / Helen L. Lowe ... [et al.] -- Immune privilege and tolerance - therapeutic antibody approaches / Daron Forman ... [et al.] -- Antibody therapeutics : business achievements and business outlook / Christophe Bourrilly. |