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ABC transporters and multidrug resistance

Wiley Series in Drug Discovery and Development. Binghe Wang, Series Editor. ABC Transporters and Multidrug Resistance. Edited by. Ahcne Boumendjel. Jean Boutonnat. Jacques Robert. A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance. ATP-binding...

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Bibliographic Details
Group Author: Boumendjel, Ahcène; Boutonnat, Jean; Robert, Jacques, M.D
Published:
Literature type: Electronic eBook
Language: English
Series: Wiley series in drug discovery and development
Subjects:
ATP-Binding Cassette Transporters
Drug resistance in cancer cells
SCIENCE / Life Sciences / Biochemistry
Multidrug Resistance-Associated Proteins
Drug Resistance, Multiple
Neoplasms > drug therapy
Electronic books
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9780470495131
Summary: Wiley Series in Drug Discovery and Development. Binghe Wang, Series Editor. ABC Transporters and Multidrug Resistance. Edited by. Ahcne Boumendjel. Jean Boutonnat. Jacques Robert. A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance. ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventua
Carrier Form: 1 online resource (xiii, 459 p.) : ill.
Bibliography: Includes bibliographical references and index.
ISBN: 9780470495124 (electronic bk.)
047049512X (electronic bk.)
Index Number: QP552
CLC: R961
Contents: ABC proteins : overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action -- ABC proteins and oncology : expression, detection, and implication of ABC proteins in hematological malignancies and solid tumors -- ABC proteins and pathogenic microorganisms -- MDR modulation through inhibition of ABC transporters : design of inhibitors and mechanism of action -- Biological and clinical aspect of multidrug resistance.

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