Screen LibraryLiver regeneration and carcinogenesis : molecular and cellular mechanisms /
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have oc...
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| Published: |
Academic Press,
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| Publisher Address: | San Diego : |
| Publication Dates: | 1995. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780123853554 |
| Summary: |
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current f |
| Carrier Form: | 1 online resource (xxiii, 402 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780123853554 0123853559 9780080535548 0080535542 |
| Index Number: | RC280 |
| CLC: | R575 |
| Contents: | Liver Regeneration, Then and Now. Hepatocyte Growth Factor (HGF) and Its Receptor (MET) in Liver Regeneration, Neoplasia, And Disease. Structure and Functions of the HGF Receptor (C-Met). Expression and Function of Growth-Induced Genes During Liver Regeneration. Stem Cells and Hepatocarcinogenesis. Contributions of Hepadnavirus Research to Our Understanding of Hepatocarcinogenesis. Apoptosis and Hepatocarcinogenesis. Liver Tumor Promotion and the Suppression of P53-Dependant Cell Cycle Checkpoint Function. Mechanisms of Liver Tumor Promotion. Hypomethylation of DNA: A Epigenetic Mechanism th |