Screen LibraryDNA, words and models
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| Main Authors: | |
|---|---|
| Group Author: | ; |
| Published: |
Cambridge University Press,
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| Publisher Address: | Cambridge, UK New York |
| Publication Dates: | 2005. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Item Description: | ADN, mots, et modaeles. |
| Carrier Form: | xx, 138 p.: ill. ; 24 cm. |
| ISBN: | 052184729X (hbk.) |
| Index Number: | Q523 |
| CLC: |
Q523-3 Q3-3 |
| Call Number: | Q3-3/R655 |
| Contents: |
Includes bibliographical references (p. 134-136) and index. Introduction. The context -- Randomness and models -- A bit of biology -- Simple models for biological sequences. Why a model? -- Permutation model -- Bernoulli model -- Introduction to Markov chain models. Assumptions -- Markov chain order 1 -- Markov chain order m -- Estimation of the parameters -- Taking heterogeneities into account. Phased chains -- Piecewise homogeneous Markov chains -- Translation conditional models -- Statistical properties of word occurrences. Count -- Positions and distances -- Distribution along the sequence -- Words with unexpected frequencies. Exact distribution and approximations -- Influence of the model -- Over-representations of Chi sites in E. coli and H. influenzae -- Under-representation of palindromes of length 6 in E. coli and in the phage Lambda -- Words with unexpected locations. Chi sites in the genome of H. influenzae -- Distribution of palindromes in E. coli's genome -- Detection of promoter sites in B. subtilis -- The last word. |