Screen LibraryDiabetes and viruses /
Diabetes, in all of its forms, now constitutes a growing health concern, affecting all segments of the world's population. There is great interest in the factors which influence its etiology and progression. Among these, a number of viruses feature prominently. Hindered by technological limitat...
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| Corporate Authors: | |
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| Group Author: | |
| Published: |
Springer,
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| Publisher Address: | New York, NY : |
| Publication Dates: | 2013. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-1-4614-4051-2 |
| Summary: |
Diabetes, in all of its forms, now constitutes a growing health concern, affecting all segments of the world's population. There is great interest in the factors which influence its etiology and progression. Among these, a number of viruses feature prominently. Hindered by technological limitations, research into this relationship has hitherto been scarce. Recent advances, however, have opened up the field and there is a burgeoning body of literature on the subject. Unfortunately, this literature has been diffuse and often difficult to access.For the first time, this book compiles the views of many of the world's experts in the field. It addresses questions, ranging from how viruses may destroy or modify the function of pancreatic islets; to which viruses are the most likely culprits; to whether vaccines or etiologic therapies might be used to prevent virus-induced diabetes. Diabetes and Viruses is the first comprehensive volume on an important and expanding field of research that is of interest to clinicians, healthcare managers, epidemiologists, veterinarians, and basic scientists. |
| Carrier Form: | 1 online resource |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781461440512 (electronic bk.) 1461440513 (electronic bk.) |
| Index Number: | RC660 |
| CLC: | R587.1 |
| Contents: |
Background and Pathogenesis -- Historical Background: Earlier Studies on the Connexion Between Viruses and Diabetes / Viruses and Autoimmune Diabetes: A History / Genetics of Type 1 Diabetes / Non-Genetic Factors in the Pathogenesis of Type 1 Diabetes / Studies in Animals -- Encephalomyocarditis Virus / Enteroviruses in the Mouse Model of Type 1 Diabetes / Viruses and Autoimmune Diabetes in Rats / Reovirus / Ljungan Virus and Diabetes / Virus-Related Diabetes in Cattle / Studies in Humans -- Epidemiology of Viruses in Type 1 Diabetes: Seasonal Incidence, Family Studies, Clustering / Molecular Biology and Classification of Enteroviruses / Laboratory Diagnosis of Enterovirus Infection: Optimal Methods for Studies of Diabetes / Enterovirus Immunity and the "Hygiene Hypothesis" / Enteroviruses in Blood / Coxsackieviruses and Insulitis / Viruses in the Human Pancreas / Rotavirus and Type 1 Diabetes / Viruses, Diabetes, and Autoimmunity: Studies of Subjects at Genetic Risk for Type 1 Diabetes / Type 1 Diabetes in the Tropics: A Link with Enterovirus Infections / Diabetes and Viruses in Australia and the Asia-Pacific Region / Fulminant Type 1 Diabetes in Japan / Evaluation of causality in human studies -- Defining Causal Relationships Between Viral Infections and Human Diabetes / The JDRF Network for the Pancreatic Organ Donor with Diabetes (nPOD): A novel Resource and Study Approach in Type 1 Diabetes Research / Possible Mechanisms -- Virus-Induced Models for Type 1 Diabetes in Mice / The Role of T Lymphocytes in the Pathogenesis of Autoimmune Type 1 Diabetes: Implications for Potential Virus-Mediated Pathways / Innate Immune Responses to Viruses Inducing Diabetes / Enterovirus Infection of Cultured Human Pancreatic Islets / Innate Immunity of Human Pancreatic Islets Infected with Different Enterovirus Types / Antibody-Dependent Enhancement of Coxsackievirus-B Infection: Role in the Pathogenesis of Type 1 Diabetes / Perspectives -- Speculation on Prevention of Type 1 Diabetes / Viruses as Major Environmental Factors in the Induction of Diabetes / Reflections on Viruses and Diabetes Mellitus / |