Analytical methods for therapeutic drug monitoring and toxicology
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities det...
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Published: |
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Literature type: | Electronic eBook |
Language: | English |
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Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9780470909799 |
Summary: |
This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also gas chromatography (GC), immunoassay, electrophoresis, ultra performance liquid chromatogr. |
Carrier Form: | 1 online resource (xiv, 502 pages) |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9780470909782 (electronic bk.) 0470909781 (electronic bk.) 9780470909799 (electronic bk.) 047090979X (electronic bk.) |
Index Number: | RS189 |
CLC: | R917 |
Contents: | US adopted name -- Drug category -- Chemical name -- Other names -- Molecular formula -- Molecular weight -- CAS number -- Appearance -- Solubilities -- pKa value(s) -- Individual(s) who developed or published the method -- Drug that was analyzed -- Description of analytical system components -- Description of major operating parameters -- Standard solution preparation -- Sample preparation (dilution, liquid-liquid or SPE extraction, derivatization, etc.) -- Dynamic concentration range of the calibration curve -- Correlation coefficient and linearity -- Coefficient of variation of the assay -- Intraday and interday coefficients of variation of samples -- Limit of detection and limit of quantification -- Interference. |